Difference between revisions of "WalR"

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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
  
=== Genes controlled by WalR {{PubMed|17581128}}===
 
* '''Activation by WalR:''' ''[[cwlO]]'', ''[[lytE]]'', ''[[ydjM]]'', ''[[yocH]]'', ''[[ftsA]]-[[ftsZ]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10878122 PubMed], ''[[tagA]]-[[tagB]]'' {{PubMed|12950927}},  ''[[tagD]]-[[tagE]]-[[tagF]]'' {{PubMed|12950927}}
 
* '''Repression by WalR:''' ''[[iseA]]'', ''[[yjeA]]''
 
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[yycJ]]-[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
+
* '''Operon:''' ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  

Revision as of 10:46, 23 December 2010

  • Description: two-component response regulator, controls cell wall metabolism

Gene name walR
Synonyms yycF
Essential yes PubMed
Product two-component response regulator
Function control of cell wall metabolism
MW, pI 27 kDa, 4.876
Gene length, protein length 705 bp, 235 aa
Immediate neighbours walK, trnY-Phe
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YycF context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall/ other, transcription factors and their control, essential genes, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU40410

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component transcription regulators
  • Paralogous protein(s):


Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by WalK on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 2D1V (DNA binding domain), 2ZWM (receiver domain)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during vegetative growth, repressed during stationary phase PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original Publications