Difference between revisions of "NucA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || genetic transformation, DNA uptake  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || genetic transformation, DNA uptake  
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 4.677   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 4.677   

Revision as of 14:17, 11 December 2010

  • Description: membrane-associated nuclease, catalyzes DNA cleavage during transformation

Gene name nucA
Synonyms comI
Essential no
Product membrane-associated nuclease
Function genetic transformation, DNA uptake
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 16 kDa, 4.677
Gene length, protein length 441 bp, 147 aa
Immediate neighbours nin, tlpC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NucA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

genetic competence, membrane proteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU03430

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot), integral membrane protein PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: ComK: transcription activation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References