AtpA

• Description: ATP synthase (subunit alpha)
  
  

Gene name	atpA
Synonyms
Essential	no
Product	ATP synthase (subunit alpha))
Function	ATP synthesis
MW, pI	54 kDa, 5.04
Gene length, protein length	1506 bp, 502 aa
Immediate neighbours	atpG, atpH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ATP synthesis, membrane proteins, phosphoproteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU36830

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + H₂O + H⁺(In) = ADP + phosphate + H⁺(Out) (according to Swiss-Prot) see a video

• Protein family: ATPase alpha/beta chains family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on ser/ thr/ tyr PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot), membrane PubMed

Database entries

• Structure:

• UniProt: P37808

• KEGG entry: [3]

• E.C. number: 3.6.3.14

Expression and regulation

• Operon: atpI-atpB-atpE-atpF-atpH-atpA-atpG-atpD-atpC PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: