Difference between revisions of "Easter egg"
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− | * '''Description:''' | + | * '''Description:''' RNA component of [[RNase]] P <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
− | |'' | + | |''rnpB'' |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''rnaP '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || RNA component of ribonuclease P <br/>([[RNase]] P) (catalytic subunit, ribozyme) |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || cleavage of precursor sequences <br/>from the 5' ends of pre-tRNAs |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Gene length''' || | + | |style="background:#ABCDEF;" align="center"| '''Gene length''' || 401 bp |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ypsC]]'', ''[[ypsB]]'' |
|- | |- | ||
− | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ | + | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/rnpB_nucleotide.txt Gene sequence (+200bp) ]''' |
+ | |||
|- | |- | ||
− | |colspan="2" | '''Genetic context''' <br/> [[Image: | + | |colspan="2" | '''Genetic context''' <br/> [[Image:rnpB_context.gif]] |
+ | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
|} | |} | ||
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__TOC__ | __TOC__ | ||
− | <br/><br/> | + | <br/><br/><br/><br/><br/><br/><br/> |
− | |||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
− | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[Rnases]]}}, |
+ | {{SubtiWiki category|[[translation]]}}, | ||
{{SubtiWiki category|[[ncRNA]]}} | {{SubtiWiki category|[[ncRNA]]}} | ||
Line 44: | Line 46: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
− | + | === Database entries === | |
+ | |||
+ | * '''DBTBS entry:''' no entry | ||
+ | |||
+ | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG00045] | ||
+ | |||
+ | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2A64 2A64] (from Geobacillus stearothermophilus), [http://www.rcsb.org/pdb/explore.do?structureId=1NBS 1NBS] (specificity domain) | ||
− | |||
− | + | =The RNA= | |
− | * ''' | + | * '''Biological activity:''' 5' end maturation of precursor tRNAs |
− | |||
− | |||
− | + | * '''RNA family:''' | |
+ | * '''cofactor:''' divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA {{PubMed|20434461}} | ||
+ | * '''interaction:''' [[RnpA]]-RnpB | ||
+ | === Additional information=== | ||
=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' | + | * '''Operon:''' |
− | * '''Sigma factor:''' | + | * '''Sigma factor:''' |
− | * '''Regulation:''' | + | * '''Regulation:''' |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Line 80: | Line 88: | ||
* '''lacZ fusion:''' | * '''lacZ fusion:''' | ||
+ | * '''GFP fusion:''' | ||
− | + | * '''two-hybrid system:''' | |
− | + | * '''Antibody:''' | |
− | [[Roland Hartmann]] | + | =Labs working on this gene/RNA= |
+ | * [[Carol Fierke]], University of Michigan, Ann Arbor, USA [https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=fierke homepage] | ||
+ | * [[Roland Hartmann]], Marburg University, Germany [http://www.pharmazie.uni-marburg.de/pharmchem/akhartmann/ag_hartmann.htm homepage] | ||
=Your additional remarks= | =Your additional remarks= | ||
=References= | =References= | ||
+ | ==Reviews== | ||
+ | <pubmed> 19215776 17868095 14691942 16650980 16980936 16679018 14550630 </pubmed> | ||
− | <pubmed> | + | ==Original Publications== |
+ | <pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747 19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed> | ||
[[Category:small RNA]] | [[Category:small RNA]] |
Revision as of 13:50, 8 December 2010
- Description: RNA component of RNase P
Gene name | rnpB |
Synonyms | rnaP |
Essential | no |
Product | RNA component of ribonuclease P (RNase P) (catalytic subunit, ribozyme) |
Function | cleavage of precursor sequences from the 5' ends of pre-tRNAs |
Gene length | 401 bp |
Immediate neighbours | ypsC, ypsB |
Gene sequence (+200bp) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
The RNA
- Biological activity: 5' end maturation of precursor tRNAs
- RNA family:
- cofactor: divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA PubMed
- interaction: RnpA-RnpB
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/RNA
- Carol Fierke, University of Michigan, Ann Arbor, USA homepage
- Roland Hartmann, Marburg University, Germany homepage
Your additional remarks
References
Reviews
Original Publications