KatX

• Description: catalase, general stress protein
  
  

Gene name	katX
Synonyms	yxlI
Essential	no
Product	catalase (major catalase in spores)
Function	detoxification (degradation) of hydrogen peroxide
MW, pI	62 kDa, 5.341
Gene length, protein length	1641 bp, 547 aa
Immediate neighbours	aag, yxlH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38630

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

sporulation proteins, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2 H₂O₂ = O₂ + 2 H₂O (according to Swiss-Prot)

• Protein family: catalase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94377

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: katX PubMed

• Sigma factor: SigB PubMed, SigF PubMed

• Regulation:
  • expressed early during sporulation in the forespore (SigF, RsfA) PubMed
  • induced by stress (SigB) PubMed

• Regulatory mechanism:
  • RsfA: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: