BdhA

• Description: acetoine/ butanediol dehydrogenase
  
  

Gene name	bdhA
Synonyms	ydjL
Essential	no
Product	acetoine/ butanediol dehydrogenase
Function	overflow metabolism, fermentation
MW, pI	37 kDa, 4.805
Gene length, protein length	1038 bp, 346 aa
Immediate neighbours	iolT, ydjM
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU06240

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

carbon core metabolism

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: formation of butanediol from acetoin PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34788

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: bdhA (according to DBTBS)

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)

Wayne L Nicholson
The Bacillus subtilis ydjL (bdhA) gene encodes acetoin reductase/2,3-butanediol dehydrogenase.
Appl Environ Microbiol: 2008, 74(22);6832-8
[PubMed:18820069] [WorldCat.org] [DOI] (I p)