Difference between revisions of "SigI"
| Line 1: | Line 1: | ||
| − | * '''Description:''' RNA polymerase ECF [[sigma factor]] SigI <br/><br/> | + | * '''Description:''' [[RNA polymerase]] ECF [[sigma factor]] SigI <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || RNA polymerase ECF [[sigma factor]] SigI | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[RNA polymerase]] ECF [[sigma factor]] SigI |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || control of a class of heat shock genes | |style="background:#ABCDEF;" align="center"|'''Function''' || control of a class of heat shock genes | ||
| Line 78: | Line 78: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[RsgI]]-[[SigI]], the interaction inhibits SigI activity [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | + | * '''Interactions:''' |
| + | ** [[RsgI]]-[[SigI]], the interaction inhibits SigI activity [http://www.ncbi.nlm.nih.gov/sites/entrez/17185538 PubMed] | ||
| + | ** [[SigI]]-[[RpoB]]-[[RpoC]] | ||
* '''Localization:''' | * '''Localization:''' | ||
Revision as of 18:16, 21 August 2010
- Description: RNA polymerase ECF sigma factor SigI
| Gene name | sigI |
| Synonyms | ykoZ |
| Essential | no |
| Product | RNA polymerase ECF sigma factor SigI |
| Function | control of a class of heat shock genes |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 29 kDa, 8.306 |
| Gene length, protein length | 753 bp, 251 aa |
| Immediate neighbours | ykoY, rsgI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU13450
Phenotypes of a mutant
temperature-sensitive growth on agar plates PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Members of the SigI regulon
gsiB PubMed, mreBH, bcrC PubMed
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: O31654
- KEGG entry: [3]
- E.C. number:
Additional information
overexpression of SigI suppresses mreB mreBH mbl mutants PubMed
Expression and regulation
- Regulation: induced by heat PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
