Difference between revisions of "BshA"
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| − | * '''Description:''' | + | * '''Description:''' L-malic acid glycosyltransferase, involved in bacillithiol synthesis <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || L-malic acid glycosyltransferase |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of bacillithiol |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 6.149 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 6.149 | ||
Revision as of 07:56, 7 April 2010
- Description: L-malic acid glycosyltransferase, involved in bacillithiol synthesis
| Gene name | BshA |
| Synonyms | jojH, ypjH |
| Essential | no |
| Product | L-malic acid glycosyltransferase |
| Function | biosynthesis of bacillithiol |
| MW, pI | 41 kDa, 6.149 |
| Gene length, protein length | 1131 bp, 377 aa |
| Immediate neighbours | cca, ypjG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU22460
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: UDP-GlcNAc + L-malate = GlcNAc(α1→2)L-malate [2]; also uses D-malate as a substrate, but with much lower affinity
- Protein family: NamA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P42982
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: bshA::mls available in John_Helmann lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
