Difference between revisions of "NdoA"
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* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' the activity is inhibited by the interaction with [[NdoAI]] {{PubMed|17416361}} |
| − | * '''Interactions:''' | + | * '''Interactions:''' [[NdoAI]]-[[NdoA|EndoA]] {{PubMed|17416361}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 118: | Line 118: | ||
=References= | =References= | ||
| − | <pubmed>15882409,, </pubmed> | + | <pubmed>15882409,17416361, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 21:21, 6 April 2010
- Description: RNase EndoA, MazF family toxin, cleaves cellular mRNAs at specific, but frequently occuring sites
| Gene name | ndoA |
| Synonyms | ydcE |
| Essential | no |
| Product | endoribonuclease EndoA, MazF family toxin |
| Function | plasmid partition |
| MW, pI | 12 kDa, 4.892 |
| Gene length, protein length | 348 bp, 116 aa |
| Immediate neighbours | ndoAI, rsbR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU04660
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: pemK family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Localization:
Database entries
- Structure: 1NE8
- UniProt: P96622
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Shivangi Agarwal, Shivani Agarwal, Rakesh Bhatnagar
Identification and characterization of a novel toxin-antitoxin module from Bacillus anthracis.
FEBS Lett: 2007, 581(9);1727-34
[PubMed:17416361]
[WorldCat.org]
[DOI]
(P p)
Olivier Pellegrini, Nathalie Mathy, Arhonda Gogos, Lawrence Shapiro, Ciarán Condon
The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor.
Mol Microbiol: 2005, 56(5);1139-48
[PubMed:15882409]
[WorldCat.org]
[DOI]
(P p)
