Difference between revisions of "Ddl"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2YZG 2YZG] (from ''Thermus thermophilus hb8 mutant'', 40% identity, 53% similarity) | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2YZG 2YZG] (from ''Thermus thermophilus hb8 mutant'', 40% identity, 53% similarity) |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P96612 P96612] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P96612 P96612] | ||
Revision as of 11:44, 18 February 2010
- Description: D-alanine-D-alanine ligase
| Gene name | ddl |
| Synonyms | ddlA |
| Essential | yes PubMed |
| Product | D-alanine-D-alanine ligase |
| Function | peptidoglycan precursor biosynthesis |
| Metabolic function and regulation of this protein in SubtiPathways: Cell wall | |
| MW, pI | 38 kDa, 4.58 |
| Gene length, protein length | 1062 bp, 354 aa |
| Immediate neighbours | ydbP, murF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU04560
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine (according to Swiss-Prot)
- Protein family: ATP-grasp domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2YZG (from Thermus thermophilus hb8 mutant, 40% identity, 53% similarity)
- UniProt: P96612
- KEGG entry: [2]
- E.C. number: 6.3.2.4
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
