Difference between revisions of "DnaI"
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| − | * '''Description:''' primosome component (helicase loader) <br/><br/> | + | * '''Description:''' primosome component (helicase loader), part of the [[replisome]] <br/><br/> |
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[DnaB]]-[[DnaI]], [[DnaC]]-[[DnaI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10844689 PubMed] | + | * '''Interactions:''' [[DnaB]]-[[DnaI]], [[DnaC]]-[[DnaI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10844689 PubMed], part of the [[replisome]]: [[PolC]]-[[HolA]]-[[HolB]]-[[DnaX]]-[[DnaN]]-[[DnaG]]-[[DnaC]]-[[DnaI]]-[[DnaD]]-[[SsbA]]-[[DnaE]]-[[PriA]]-[[DnaB]] {{PubMed|20122408}} |
* '''Localization:''' cell membrane (according to Swiss-Prot), Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] forms foci, close to oriC [http://www.ncbi.nlm.nih.gov/sites/entrez/10844689 PubMed] | * '''Localization:''' cell membrane (according to Swiss-Prot), Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] forms foci, close to oriC [http://www.ncbi.nlm.nih.gov/sites/entrez/10844689 PubMed] | ||
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=References= | =References= | ||
| − | <pubmed>19255093,10844689,12718886,11842108,, 16479537, 19744498 , 19255093 19968790 11679082 </pubmed> | + | <pubmed>19255093,10844689,12718886,11842108, 20122408, 16479537, 19744498 , 19255093 19968790 11679082 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:24, 4 February 2010
- Description: primosome component (helicase loader), part of the replisome
| Gene name | dnaI |
| Synonyms | ytxA, dnaY |
| Essential | yes PubMed |
| Product | primosome component (helicase loader) |
| Function | DNA replication |
| MW, pI | 35 kDa, 5.743 |
| Gene length, protein length | 933 bp, 311 aa |
| Immediate neighbours | ytxB, dnaB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28980
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: DnaB-DnaI, DnaC-DnaI PubMed, part of the replisome: PolC-HolA-HolB-DnaX-DnaN-DnaG-DnaC-DnaI-DnaD-SsbA-DnaE-PriA-DnaB PubMed
- Localization: cell membrane (according to Swiss-Prot), Cytoplasm (Homogeneous) PubMed forms foci, close to oriC PubMed
Database entries
- Structure: 2K7R (N-terminal domain)
- UniProt: P06567
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
