Difference between revisions of "GapA"

From SubtiWiki
Jump to: navigation, search
(Extended information on the protein)
(Extended information on the protein)
Line 33: Line 33:
 
== Extended information on the protein ==
 
== Extended information on the protein ==
  
* '''Kinetic information'''
+
* '''Kinetic information:'''
  
* '''Domains'''  
+
* '''Domains:'''  
  
* '''Modification''' Phosphorylation (STY)
+
* '''Modification:''' Phosphorylation (STY)
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
Line 45: Line 45:
 
** GapA-[[Crh]]: [[Crh|Crh(Ser-46-P)]] binds GapA resulting in a slight inhibition of enzymatic activity.
 
** GapA-[[Crh]]: [[Crh|Crh(Ser-46-P)]] binds GapA resulting in a slight inhibition of enzymatic activity.
  
* '''Localization'''
+
* '''Localization:''' membrane and cytoplasm
membrane and cytoplasm
 
  
 
== Database entries ==
 
== Database entries ==

Revision as of 16:51, 12 December 2008

  • Synonyms:
  • Description: glyceraldehyde-3-phosphate dehydrogenase, (NADH-dependent), glycolytic enzyme

The gene

Basic information

  • Coordinates:
  • Gene length:

Phenotypes of a mutant

essential

Database entries

  • DBTBS entry: [1]
  • SubtiList entry:[2]

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: glyceraldehyde-3-phosphate dehydrogenase, (NADH-dependent)
  • Protein family:
  • Paralogous protein(s): GapB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: Phosphorylation (STY)
  • Effectors of protein activity:
  • Interactions:
    • GapA-PtsH: HPr(Ser-46-P) binds GapA resulting in a slight inhibition of enzymatic activity.
    • GapA-Crh: Crh(Ser-46-P) binds GapA resulting in a slight inhibition of enzymatic activity.
  • Localization: membrane and cytoplasm

Database entries

  • Structure
  • Swiss prot entry
  • KEGG entry

Expression and regulation

  • Regulation: CggR represses the operon in the absence of glycolytic sugars
  • Regulatory mechanism: repression

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • Antibody:


Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. [3]