Difference between revisions of "PbuO"
| Line 89: | Line 89: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' ''[[pbuO]]'' {{PubMed|9387221}} | |
| − | * '''Operon:''' | ||
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed in the presence of purine nucleotides ([[PurR]]) | + | ** repressed in the presence of purine nucleotides ([[PurR]]) {{PubMed|11591660,2536750}} |
| − | |||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | + | ** [[PurR]]: transcription repression (molecular inducer: PRPP) {{PubMed|11591660,2536750}} | |
| − | ** [[PurR]]: transcription repression (molecular inducer: PRPP) | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 124: | Line 121: | ||
=References= | =References= | ||
| − | <pubmed>11591660,, | + | <pubmed>11591660,2536750 ,9387221 , </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:45, 19 December 2009
| Gene name | pbuO |
| Synonyms | ytiP |
| Essential | no |
| Product | unknown |
| Function | unknown |
| Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation) | |
| MW, pI | 45 kDa, 7.484 |
| Gene length, protein length | 1296 bp, 432 aa |
| Immediate neighbours | ytjP, ythQ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29990
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): PbuG
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O34978
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
H H Saxild, K Brunstedt, K I Nielsen, H Jarmer, P Nygaard
Definition of the Bacillus subtilis PurR operator using genetic and bioinformatic tools and expansion of the PurR regulon with glyA, guaC, pbuG, xpt-pbuX, yqhZ-folD, and pbuO.
J Bacteriol: 2001, 183(21);6175-83
[PubMed:11591660]
[WorldCat.org]
[DOI]
(P p)
Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221]
[WorldCat.org]
[DOI]
(P p)
D J Ebbole, H Zalkin
Interaction of a putative repressor protein with an extended control region of the Bacillus subtilis pur operon.
J Biol Chem: 1989, 264(6);3553-61
[PubMed:2536750]
[WorldCat.org]
(P p)
