Difference between revisions of "AnsR"
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| − | * '''Description:''' transcription repressor of the '' | + | * '''Description:''' transcription repressor of the ''[[ansA]]-[[ansB]]'' operon<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator (Xre family) | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator ([[Xre family]]) |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || negative regulation of the ''[[ansA]]-[[ansB]]'' operon | |style="background:#ABCDEF;" align="center"|'''Function''' || negative regulation of the ''[[ansA]]-[[ansB]]'' operon | ||
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''ansR'' | + | * '''Operon:''' ''ansR'' {{PubMed|8478318}} |
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced in the presence of asparagine ([[AnsR]]){{PubMed|11914346}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[AnsR]]: negative autoregulation {{PubMed|11914346}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 122: | ||
=References= | =References= | ||
| − | <pubmed>8478318,, </pubmed> | + | <pubmed>8478318,11914346 , </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 21:08, 18 November 2009
| Gene name | ansR |
| Synonyms | |
| Essential | no |
| Product | transcriptional regulator (Xre family) |
| Function | negative regulation of the ansA-ansB operon |
| Metabolic function and regulation of this protein in SubtiPathways: Asp, Asn | |
| MW, pI | 13 kDa, 4.807 |
| Gene length, protein length | 348 bp, 116 aa |
| Immediate neighbours | ansA, yqxK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU23590
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: Q07683
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ansR PubMed
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Susan H Fisher, Lewis V Wray
Bacillus subtilis 168 contains two differentially regulated genes encoding L-asparaginase.
J Bacteriol: 2002, 184(8);2148-54
[PubMed:11914346]
[WorldCat.org]
[DOI]
(P p)
D Sun, P Setlow
Cloning and nucleotide sequence of the Bacillus subtilis ansR gene, which encodes a repressor of the ans operon coding for L-asparaginase and L-aspartase.
J Bacteriol: 1993, 175(9);2501-6
[PubMed:8478318]
[WorldCat.org]
[DOI]
(P p)
