Difference between revisions of "SpoIVFB"
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' processing of pro-sigma-K to active [[SigK]] | + | * '''Catalyzed reaction/ biological activity:''' processing of pro-sigma-K to active [[SigK]] {{PubMed|19805276}} |
* '''Protein family:''' peptidase M50B family (according to Swiss-Prot) | * '''Protein family:''' peptidase M50B family (according to Swiss-Prot) | ||
| Line 63: | Line 63: | ||
* '''Domains:''' | * '''Domains:''' | ||
| + | ** C-terminal cystathionine-beta-synthase (CBS) domain, this domain binds ATP {{PubMed|19805276}} | ||
* '''Modification:''' | * '''Modification:''' | ||
| Line 68: | Line 69: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' ATP regulates substrate access to the active site and renders cleavage sensitive to the cellular energy level {{PubMed|19805276}} |
| − | * '''Interactions:''' [[SpoIVFB]]-pro[[SigK]] | + | * '''Interactions:''' [[SpoIVFB]]-pro[[SigK]] {{PubMed|19805276}} |
* '''Localization:''' cell membrane | * '''Localization:''' cell membrane | ||
| Line 118: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287, 16818230 </pubmed> | + | <pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287, 16818230 19805276 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:54, 8 October 2009
- Description: intramembrane metalloprotease, processing of pro-sigma-K to active SigK
| Gene name | spoIVFB |
| Synonyms | |
| Essential | no |
| Product | intramembrane metalloprotease |
| Function | processing of pro-sigma-K to active SigK |
| MW, pI | 33 kDa, 8.483 |
| Gene length, protein length | 864 bp, 288 aa |
| Immediate neighbours | rplU, spoIVFA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU27970
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: peptidase M50B family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- C-terminal cystathionine-beta-synthase (CBS) domain, this domain binds ATP PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity: ATP regulates substrate access to the active site and renders cleavage sensitive to the cellular energy level PubMed
- Localization: cell membrane
Database entries
- Structure:
- UniProt: P26937
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
