Difference between revisions of "SwrAA/1"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
* '''Description:''' control of motility,  enhances sigD transcription <br/><br/>
+
* '''Description:''' control of motility,  enhances [[sigD]] transcription <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 122: Line 122:
 
=References=
 
=References=
  
<pubmed>16357223,19389763,16030230,18567663,15066026,, 19389763 </pubmed>
+
<pubmed>16357223,19389763,16030230,18567663,15066026,, 19389763 19749039 </pubmed>
  
 
[[Category:Pseudogenes]]
 
[[Category:Pseudogenes]]

Revision as of 08:45, 15 September 2009

  • Description: control of motility, enhances sigD transcription

Gene name swrAA
Synonyms yvzD
Essential no
Product swarming motility protein
Function essential for swarming differentiation on solid surfaces
MW, pI 13 kDa, 8.4
Gene length, protein length 336 bp, 112 aa
Immediate neighbours minJ, ctpB
Gene sequence (+200bp) Protein sequence
Genetic context
YvzD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

This protein is functional in undomesticated strains of B.subtilis but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of B.subtilis are unable to swarm.

The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of swrAA was predicted to be an ORF (yvzD) by the genome project.

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References