Difference between revisions of "ThiS"
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Revision as of 09:37, 21 July 2009
- Description: hydroxyethylthiazole phosphate biosynthesis
| Gene name | thiS |
| Synonyms | yjbS |
| Essential | no |
| Product | unknown |
| Function | biosynthesis of thiamine |
| MW, pI | 7 kDa, 5.501 |
| Gene length, protein length | 198 bp, 66 aa |
| Immediate neighbours | thiO, thiG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU11680
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- Swiss prot entry: O31617
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ethan C Settembre, Pieter C Dorrestein, Huili Zhai, Abhishek Chatterjee, Fred W McLafferty, Tadhg P Begley, Steven E Ealick
Thiamin biosynthesis in Bacillus subtilis: structure of the thiazole synthase/sulfur carrier protein complex.
Biochemistry: 2004, 43(37);11647-57
[PubMed:15362849]
[WorldCat.org]
[DOI]
(P p)
