Difference between revisions of "ThiD"

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(moved ThiD to PdxK over redirect)
 
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#REDIRECT [[PdxK]]
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* '''Description:''' 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase<br/><br/>
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{| align="right" border="1" cellpadding="2"
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|-
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
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|''thiD''
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|-
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yjbV''
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|-
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || 4-amino-5-hydroxymethyl-2-methylpyrimidine<br/>pyrophosphate kinase
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|-
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of thiamine pyrophosphate (TPP)
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|-
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 5.709 
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|-
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 813 bp, 271 aa
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|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[thiF]]'', ''[[fabI]]''
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|-
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yjbV_nucleotide.txt    Gene sequence      (+200bp)  ]'''
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yjbV_protein.txt Protein sequence]'''
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|-
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|colspan="2" | '''Genetic context''' <br/> [[Image:yjbV_context.gif]]
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<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|-
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|}
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__TOC__
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<br/><br/>
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=The gene=
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=== Basic information ===
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* '''Locus tag:''' BSU11710
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===Phenotypes of a mutant ===
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=== Database entries ===
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* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tenAI-goxB-thiSGF-yjbV.html]
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* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13151]
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=== Additional information===
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=The protein=
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=== Basic information/ Evolution ===
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* '''Catalyzed reaction/ biological activity:'''
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* '''Protein family:'''
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* '''Paralogous protein(s):''' [[PdxK]]
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=== Extended information on the protein ===
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* '''Kinetic information:'''
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* '''Domains:'''
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* '''Modification:'''
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* '''Cofactor(s):'''
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* '''Effectors of protein activity:'''
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* '''Interactions:'''
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* '''Localization:'''
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=== Database entries ===
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* '''Structure:'''
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* '''Swiss prot entry:'''
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU11710]
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* '''E.C. number:'''
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=== Additional information===
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=Expression and regulation=
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* '''Operon:'''
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* '''[[Sigma factor]]:'''
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* '''Regulation:'''
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* '''Regulatory mechanism:'''
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* '''Additional information:'''
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=Biological materials =
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* '''Mutant:'''
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* '''Expression vector:'''
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* '''lacZ fusion:'''
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* '''GFP fusion:'''
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* '''two-hybrid system:'''
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* '''Antibody:'''
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 +
=Labs working on this gene/protein=
 +
 
 +
=Your additional remarks=
 +
 
 +
=References=
 +
 
 +
<pubmed>14973012,, </pubmed>

Revision as of 08:34, 13 July 2009

  • Description: 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase

Gene name thiD
Synonyms yjbV
Essential no
Product 4-amino-5-hydroxymethyl-2-methylpyrimidine
pyrophosphate kinase
Function biosynthesis of thiamine pyrophosphate (TPP)
MW, pI 28 kDa, 5.709
Gene length, protein length 813 bp, 271 aa
Immediate neighbours thiF, fabI
Gene sequence (+200bp) Protein sequence
Genetic context
YjbV context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU11710

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): PdxK

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Joo-Heon Park, Kristin Burns, Cynthia Kinsland, Tadhg P Begley
Characterization of two kinases involved in thiamine pyrophosphate and pyridoxal phosphate biosynthesis in Bacillus subtilis: 4-amino-5-hydroxymethyl-2methylpyrimidine kinase and pyridoxal kinase.
J Bacteriol: 2004, 186(5);1571-3
[PubMed:14973012] [WorldCat.org] [DOI] (P p)

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