Difference between revisions of "BacA"
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || bacilysin biosynthesis protein, dehydratase | |style="background:#ABCDEF;" align="center"| '''Product''' || bacilysin biosynthesis protein, dehydratase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || bacilysin | + | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the antibiotic bacilysin |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 7.896 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 7.896 | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[bacA]]-[[bacB]]-[[bacC]]-[[bacD]]-[[bacE]]-[[bacF]]'' {{PubMed|12372825}} |
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CodY]]: transcription repression {{PubMed|12372825}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 118: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed>15609023,12399481,, </pubmed> | + | <pubmed>15609023,12399481,12372825 , </pubmed> |
Revision as of 21:25, 9 July 2009
- Description: bacilysin biosynthesis protein, dehydratase
| Gene name | bacA |
| Synonyms | ywfB, ipa-80d |
| Essential | no |
| Product | bacilysin biosynthesis protein, dehydratase |
| Function | biosynthesis of the antibiotic bacilysin |
| MW, pI | 23 kDa, 7.896 |
| Gene length, protein length | 612 bp, 204 aa |
| Immediate neighbours | bacB, ywfA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU37740
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P39638
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Gerhard Steinborn, Mohammad-Reza Hajirezaei, Jürgen Hofemeister
bac genes for recombinant bacilysin and anticapsin production in Bacillus host strains.
Arch Microbiol: 2005, 183(2);71-9
[PubMed:15609023]
[WorldCat.org]
[DOI]
(P p)
Min Cao, John D Helmann
Regulation of the Bacillus subtilis bcrC bacitracin resistance gene by two extracytoplasmic function sigma factors.
J Bacteriol: 2002, 184(22);6123-9
[PubMed:12399481]
[WorldCat.org]
[DOI]
(P p)
Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Kozo Ochi
Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.
J Biol Chem: 2003, 278(4);2169-76
[PubMed:12372825]
[WorldCat.org]
[DOI]
(P p)
