Difference between revisions of "GltC"
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Linc Sonenshein, Tufts University, Boston, MA, USA [http://www.tufts.edu/sackler/microbiology/faculty/sonenshein/index.html] | Linc Sonenshein, Tufts University, Boston, MA, USA [http://www.tufts.edu/sackler/microbiology/faculty/sonenshein/index.html] | ||
| − | Jörg Stülke, University of Göttingen, Germany | + | [[Stülke|Jörg Stülke]], University of Göttingen, Germany |
[http://wwwuser.gwdg.de/~genmibio/stuelke.html] | [http://wwwuser.gwdg.de/~genmibio/stuelke.html] | ||
=References= | =References= | ||
Revision as of 19:42, 10 December 2008
- Synonyms:
- Description: Transcriptional activator of the gltAB operon. Activates expression of the operon in the absence of arginine.
Contents
The gene
Basic information
- Coordinates:
- Gene length:
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of the gltAB operon
- Protein family: LysR-type transcription regulator
- Paralogous protein(s): none, but there are 19 members of the LysR family in B. subtilis
Database entries
- Structure
- Swiss prot entry
- KEGG entry
Extended information on the protein
- Kinetic information
- Domains DNA-binding helix-turn-helix motif: AA 18 ... 37
- Modification
- Effectors of protein activity:2-oxoglutarate
- Interactions:
- Localization
Expression and Regulation
- Operon: gltC [3]
- Sigma factor: SigA [4]
- Regulation: autoregulation by GltC [5]
- Regulatory mechanism: autorepression
Biological Materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- Antibody: available in Stülke lab
Phenotypes of a Mutant
Additional remarks
- Labs working on this gene/protein:
Linc Sonenshein, Tufts University, Boston, MA, USA [6]
Jörg Stülke, University of Göttingen, Germany [7]
