ZapA - Revision history

134.76.38.147 at 14:27, 2 April 2014

2014-04-02T14:27:36Z

Jstuelk at 18:13, 21 December 2013

2013-12-21T18:13:40Z

134.76.70.252 at 14:19, 18 November 2013

2013-11-18T14:19:15Z

Jstuelk at 16:56, 27 May 2013

2013-05-27T16:56:49Z

134.76.70.252 at 14:13, 16 May 2013

2013-05-16T14:13:13Z

134.76.70.252 at 10:57, 14 May 2013

2013-05-14T10:57:03Z

134.76.70.252 at 13:32, 13 May 2013

2013-05-13T13:32:11Z

134.76.70.252 at 14:41, 7 August 2012

2012-08-07T14:41:29Z

134.76.70.252 at 10:34, 20 April 2012

2012-04-20T10:34:23Z

134.76.70.252 at 14:47, 16 April 2012

2012-04-16T14:47:42Z

← Older revision		Revision as of 14:27, 2 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' positive modulator of [[FtsZ]] Z ring assembly and stability <br/><br/>~~	+	{{#bank: ZapA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''zapA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' yshA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| Z-ring-associated protein~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| control of Z-ring formation~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28610 zapA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ZapA ZapA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 9 kDa, 7.17~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 255 bp, 85 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yshB]]'', ''[[rnhC]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28610 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28610 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28610 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yshA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yshA_2925640_2925897_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:zapA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28610]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[cell division]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU28610
−
−	~~===Phenotypes of a mutant ===~~
−	* a ''[[zapA]] [[ezrA]]'' double mutant forms filamentous cells {{PubMed\|16420366}}
−	* a ''[[yvcL]] [[zapA]]'' double mutant grows poorly, and the cells are filamentous (due to a defect in Z ring assembly) {{PubMed\|24097947}}
−	* the defects of the ''[[yvcL]] [[zapA]]'' double mutant can be suppressed by inactivation of either ''[[gtaB]]'', ''[[pgcA]]'', or ''[[ugtP]]'' {{PubMed\|24097947}}
−
−	~~=== Database entries ===~~
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12325]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' Type 2 subfamily (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** forms a dimer through its extensive coiled-coil region, [[FtsZ]]-[[ZapA]] {{PubMed\|19843223}}
−
−	* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
−
−	~~=== Database entries ===~~
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P94542 P94542]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU28610]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[zapA]]-[[yshB]]'' {{PubMed\|12368265}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yshA_2925640_2925897_-1 zapA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−	** constitutively expressed {{PubMed\|23701187}}
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 19680248 19884039 23701187 </pubmed>~~
−
−	~~==Original Publications==~~
−	~~<pubmed>15288790,12368265,16420366,18588879, 19429628 19843223 24097947</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 53: / Line 53: @@
 ===Phenotypes of a mutant ===
 === Database entries ===
@@ Line 61: / Line 64: @@
 === Additional information===
 =The protein=
@@ Line 79: / Line 79: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 142: / Line 142: @@
 ==Original Publications==
-<pubmed>15288790,12368265,,18588879, 19429628 19843223 </pubmed>
+<pubmed>15288790,12368265,16420366,18588879, 19429628 19843223 24097947</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28610 zapA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ZapA ZapA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ZapA ZapA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 7.17

@@ Line 37: / Line 37: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 114: / Line 110: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yshA_2925640_2925897_-1 zapA] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''
 * '''Regulatory mechanism:'''
@@ Line 142: / Line 139: @@
 =References=
 ==Reviews==
-<pubmed> 19680248  19884039 </pubmed>
+<pubmed> 19680248  19884039 23701187 </pubmed>
 ==Original Publications==

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yshA_2925640_2925897_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:zapA_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yshA_2925640_2925897_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:zapA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28610]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yshB]]'', ''[[rnhC]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28610 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28610 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28610 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28610 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28610 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28610 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:yshA_context.gif]]

@@ Line 13: / Line 13: @@
 |-
 |style="background:#ABCDEF;" align="center"|'''Function''' || control of Z-ring formation
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ZapA ZapA]