YfkM - Revision history

134.76.70.252 at 10:11, 17 April 2014

2014-04-17T10:11:06Z

134.76.70.252 at 11:39, 8 April 2014

2014-04-08T11:39:13Z

134.76.38.147 at 13:12, 2 April 2014

2014-04-02T13:12:28Z

Jstuelk at 17:26, 14 February 2014

2014-02-14T17:26:25Z

Jstuelk at 18:12, 7 January 2014

2014-01-07T18:12:24Z

Jstuelk at 18:54, 15 September 2013

2013-09-15T18:54:24Z

134.76.70.252 at 12:47, 16 May 2013

2013-05-16T12:47:02Z

134.76.70.252 at 09:43, 14 May 2013

2013-05-14T09:43:00Z

134.76.70.252 at 12:21, 13 May 2013

2013-05-13T12:21:54Z

Raphael2215 at 11:18, 13 August 2012

2012-08-13T11:18:50Z

← Older revision		Revision as of 10:11, 17 April 2014
Line 1:		Line 1:
−	* '''Description:''' glyoxalase III-like enzyme, general stress protein, survival of salt, paraquat and ethanol stresses <br/><br/>	+	{{#bank: YfkM}}
−	{~~\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''yfkM''~~
−	\|-
−	~~\|style="background:~~#~~ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background~~:~~#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| glyoxalase III-like enzyme~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| detoxification of methylglyoxal~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07850 yfkM]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=YfkM ~~YfkM]'''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 18 kDa, 4.722~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 516 bp, 172 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yfkN]]'', ''[[yfkL]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU07850 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU07850 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU07850 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yfkM_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	~~\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkM_859745_860263_1 Expression at a glance]'''   {{PubMed\|22383849~~}~~}<br/>[[Image:yfkM_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07850]]~~
−	\|-
−	\|}

−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[general stress proteins (controlled by SigB)]]}},~~
−	~~{{SubtiWiki category\|[[resistance against oxidative and electrophile stress]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[Fur regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[SigB regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU07850
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU07850&redirect=T BSU07850]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yfkM.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12929]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−	** methylglyoxal --> D-lactate {{PubMed\|24330391}}
−
−	* '''Protein family:''' PfpI endopeptidase domain (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):''' [[YraA]]
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU07850&redirect=T BSU07850]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P80876 P80876]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU07850]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''yfkM'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkM_859745_860263_1 yfkM] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed]
−
−	* '''Regulation:'''
−	** induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed]
−	** induced upon iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
−
−	* '''Regulatory mechanism:'''
−	** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−
−	~~<pubmed>10220166, 24330391,12354229,15805528, 22582280</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 14: / Line 14: @@
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07850 yfkM]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 4.722

@@ Line 53: / Line 53: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yfkM.html]
@@ Line 88: / Line 89: @@
 === Database entries ===
 * '''Structure:'''

← Older revision		Revision as of 17:26, 14 February 2014
Line 65:		Line 65:

	* '''Catalyzed reaction/ biological activity:'''		* '''Catalyzed reaction/ biological activity:'''
		+	** methylglyoxal --> D-lactate {{PubMed\|24330391}}

	* '''Protein family:''' PfpI endopeptidase domain (according to Swiss-Prot)		* '''Protein family:''' PfpI endopeptidase domain (according to Swiss-Prot)

@@ Line 1: / Line 1: @@
-* '''Description:''' general stress protein, survival of salt, paraquat and ethanol  stresses <br/><br/>
+* '''Description:''' glyoxalase III-like enzyme, general stress protein, survival of salt, paraquat and ethanol  stresses <br/><br/>
 {| align="right" border="1" cellpadding="2"
 |-
@@ Line 9: / Line 9: @@
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+|style="background:#ABCDEF;" align="center"| '''Product''' || glyoxalase III-like enzyme
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || survival of stress conditions
+|style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of methylglyoxal
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07850 yfkM]
@@ Line 59: / Line 59: @@
 === Additional information===
 =The protein=
@@ Line 77: / Line 74: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
 * '''[[SubtInteract|Interactions]]:'''
 * '''[[Localization]]:'''
@@ Line 138: / Line 135: @@
 =References=
-<pubmed>10220166,,12354229,15805528, 22582280</pubmed>
+<pubmed>10220166, 24330391,12354229,15805528, 22582280</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 1: / Line 1: @@
-* '''Description:''' general stress protein, survival of salt and ethanol  stresses <br/><br/>
+* '''Description:''' general stress protein, survival of salt, paraquat and ethanol  stresses <br/><br/>
 {| align="right" border="1" cellpadding="2"
 |-
@@ Line 11: / Line 11: @@
 |style="background:#ABCDEF;" align="center"| '''Product''' || unknown
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || survival of salt and ethanol  stresses
+|style="background:#ABCDEF;" align="center"|'''Function''' || survival of stress conditions
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07850 yfkM]
@@ Line 34: / Line 34: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
 = [[Categories]] containing this gene/protein =
-{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}}
+{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
 = This gene is a member of the following [[regulons]] =
@@ Line 110: / Line 107: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkM_859745_860263_1 yfkM] {{PubMed|22383849}}
-* '''Sigma factor:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed]
+* '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed]
 * '''Regulation:'''
@@ Line 141: / Line 138: @@
 =References=
-<pubmed>10220166,,12354229,15805528, </pubmed>
+<pubmed>10220166,,12354229,15805528, 22582280</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 26: / Line 26: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkM_859745_860263_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yfkM_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkM_859745_860263_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yfkM_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07850]]
 |-
 |}

@@ Line 21: / Line 21: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yfkN]]'', ''[[yfkL]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU07850 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU07850 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU07850 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU07850 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU07850 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU07850 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:yfkM_context.gif]]