Ung - Revision history

Jstuelk at 13:41, 27 October 2014

2014-10-27T13:41:58Z

134.76.38.147 at 15:07, 2 April 2014

2014-04-02T15:07:02Z

134.76.70.252 at 09:37, 12 November 2013

2013-11-12T09:37:37Z

Jstuelk: /* References */

2013-09-13T17:13:27Z

‎References

134.76.70.252 at 14:52, 16 May 2013

2013-05-16T14:52:32Z

134.76.70.252 at 11:35, 14 May 2013

2013-05-14T11:35:02Z

134.76.70.252 at 14:09, 13 May 2013

2013-05-13T14:09:32Z

134.76.70.252 at 17:10, 7 August 2012

2012-08-07T17:10:56Z

134.76.70.252 at 11:42, 23 April 2012

2012-04-23T11:42:24Z

134.76.70.252 at 08:55, 17 April 2012

2012-04-17T08:55:41Z

← Older revision		Revision as of 13:41, 27 October 2014
Line 1:		Line 1:
−	* '''Description:~~''' uracil-DNA glycosylase <br/><br/>~~	+	{{#bank: Ung}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''ung''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''ipa-57d, ywdG ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| uracil-DNA glycosylase~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| DNA repair~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37970 ung]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=Ung Ung]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 25 kDa, 8.782~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 675 bp, 225 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[ywdH]]'', ''[[ywdF]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37970 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:ung_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ung_3897685_3898362_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:ung_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37970]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−
−
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[DNA repair/ recombination]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU37970
−
−	~~===Phenotypes of a mutant ===~~
−	* increased mutation rates {{PubMed\|22056936}}
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37970&redirect=T BSU37970]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ung.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10603]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:''' removes uracil preferentially from single-stranded DNA over double-stranded DNA, exhibiting higher preference for U:G than U:A mismatches {{PubMed\|21542855}}
−
−	* '''Protein family:''' uracil-DNA glycosylase family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[SsbA]]-[[Ung]] {{PubMed\|21170359}}
−
−	* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37970&redirect=T BSU37970]
−
−	* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3A7N 3A7N] (from ''Mycobacterium tuberculosis'', 42% identity) {{PubMed\|20693660}}
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P39615 P39615]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU37970]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''ung'' {{PubMed\|9353933}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ung_3897685_3898362_-1 ung] {{PubMed\|22383849}}
−
−	* '''Sigma factor:'''
−
−	* '''Regulation:'''
−	** expressed throughout growth and staionary phase {{PubMed\|22056936}}
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 22933559 </pubmed>~~
−	~~== Original publications ==~~
−	~~<pubmed> 9353933 20693660 22056936 21170359,21542855</pubmed>~~
−	~~[[Category:Protein-coding genes]]~~

@@ Line 58: / Line 58: @@
 * increased mutation rates {{PubMed|22056936}}
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ung.html]
@@ Line 93: / Line 94: @@
 === Database entries ===
 * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3A7N 3A7N] (from ''Mycobacterium tuberculosis'', 42% identity) {{PubMed|20693660}}

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37970 ung]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Ung Ung]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=Ung Ung]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 8.782

@@ Line 138: / Line 138: @@
 =References=
-'''Additional publications:''' {{PubMed|21170359,21542855}}
+==Reviews==
-<pubmed> 9353933 20693660 22056936</pubmed>
+<pubmed> 22933559 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ung_3897685_3898362_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ung_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ung_3897685_3898362_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ung_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37970]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywdH]]'', ''[[ywdF]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37970 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37970 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:ung_context.gif]]

@@ Line 13: / Line 13: @@
 |-
 |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Ung Ung]

@@ Line 98: / Line 98: @@
 * '''Operon:''' ''ung'' {{PubMed|9353933}}
-* '''[[Sigma factor]]:'''
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ung_3897685_3898362_-1 ung] {{PubMed|22383849}}
 * '''Regulation:'''
@@ Line 105: / Line 107: @@
 * '''Regulatory mechanism:'''
 * '''Additional information:'''
 =Biological materials =