SpoIVFB - Revision history

Jstuelk at 12:47, 10 December 2014

2014-12-10T12:47:35Z

134.76.38.147 at 14:23, 2 April 2014

2014-04-02T14:23:59Z

Jstuelk at 10:02, 3 December 2013

2013-12-03T10:02:59Z

Jstuelk: /* Reviews */

2013-11-26T12:39:55Z

‎Reviews

134.76.70.252 at 09:01, 12 November 2013

2013-11-12T09:01:44Z

Jstuelk: /* Extended information on the protein */

2013-09-03T17:49:31Z

‎Extended information on the protein

Jstuelk at 17:46, 3 September 2013

2013-09-03T17:46:00Z

Jstuelk: /* Reviews */

2013-07-31T12:23:40Z

‎Reviews

134.76.70.252 at 14:09, 16 May 2013

2013-05-16T14:09:36Z

134.76.70.252 at 10:53, 14 May 2013

2013-05-14T10:53:36Z

← Older revision		Revision as of 12:47, 10 December 2014
Line 1:		Line 1:
−	* '''Description:~~''' intramembrane metalloprotease, processing of pro-sigma-K to active [[SigK]] <br/><br/>~~	+	{{#bank: SpoIVFB}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''spoIVFB''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| intramembrane metalloprotease~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| processing of pro-sigma-K to active [[SigK]]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27970 spoIVFB]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SpoIVFB SpoIVFB]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 33 kDa, 8.483~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 864 bp, 288 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[rplU]]'', ''[[spoIVFA]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27970 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:spoIVFB_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFB_2855973_2856839_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:spoIVFB_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27970]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[sigma factors and their control]]}},~~
−	~~{{SubtiWiki category\|[[proteolysis]]}},~~
−	~~{{SubtiWiki category\|[[sporulation proteins]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[SigE regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU27970
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27970&redirect=T BSU27970]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIVFAB.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10332]
−
−	~~=== Additional information===~~
−
−
−
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:''' processing of pro-sigma-K to active [[SigK]] {{PubMed\|19805276}}
−
−	* '''Protein family:''' peptidase M50B family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−	** C-terminal cystathionine-beta-synthase (CBS) domain, this domain binds ATP {{PubMed\|19805276}}
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:''' ATP regulates substrate access to the active site and renders cleavage sensitive to the cellular energy level {{PubMed\|19805276}}
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[SpoIVFB]]-pro[[SigK]] {{PubMed\|23995631,23585539,19805276}}
−	** [[SpoIVFB]]-[[BofA]], to inhibit proteolytic activity of [[SpoIVFB]] {{PubMed\|15087499}}
−	** [[SpoIVFB]]-[[SpoIVFA]], to facilitate the recruitment of [[BofA]] to [[SpoIVFB]] {{PubMed\|11959848}}
−
−	* '''[[Localization]]:'''
−	** integral membrane protein {{PubMed\|11959848}}
−	** mother cell membrane {{PubMed\|24243021}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27970&redirect=T BSU27970]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P26937 P26937]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27970]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[spoIVFA]]-[[spoIVFB]]'' {{PubMed\|1942049}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFB_2855973_2856839_-1 spoIVFB] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigE]] {{PubMed\|15699190,1942049}}
−
−	* '''Regulation:'''
−	** expressed early during sporulation in the mother cell ([[SigE]], [[SpoIIID]]) {{PubMed\|15699190,1942049,15383836}}
−
−	* '''Regulatory mechanism:'''
−	** [[SpoIIID]]: transcription repression {{PubMed\|15383836}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 20836086 23479438 19189971 24099006 </pubmed>~~
−
−	~~==Original Publications==~~
−	~~<pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287,15383836 16818230 19805276 15699190 23585539 23995631 15087499 24243021 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 57: / Line 57: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIVFAB.html]
@@ Line 100: / Line 101: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 97: / Line 97: @@
 * '''[[Localization]]:'''
 ** integral membrane protein {{PubMed|11959848}}
-** outermost membrane surrounding the forespore {{PubMed|9078383}}
+** mother cell membrane {{PubMed|24243021}}
 === Database entries ===
@@ Line 150: / Line 150: @@
 ==Original Publications==
-<pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287,15383836 16818230 19805276 15699190 23585539 23995631 15087499</pubmed>
+<pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287,15383836 16818230 19805276 15699190 23585539 23995631 15087499 24243021 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 147: / Line 147: @@
 =References=
 ==Reviews==
-<pubmed> 20836086 23479438 19189971 </pubmed>
+<pubmed> 20836086 23479438 19189971 24099006 </pubmed>
 ==Original Publications==
 <pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287,15383836 16818230 19805276 15699190 23585539 23995631 15087499</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27970 spoIVFB]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIVFB SpoIVFB]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SpoIVFB SpoIVFB]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 8.483

← Older revision		Revision as of 17:49, 3 September 2013
Line 96:		Line 96:

	* '''[[Localization]]:'''		* '''[[Localization]]:'''
		+	** integral membrane protein {{PubMed\|11959848}}
	** outermost membrane surrounding the forespore {{PubMed\|9078383}}		** outermost membrane surrounding the forespore {{PubMed\|9078383}}

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFB_2855973_2856839_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:spoIVFB_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFB_2855973_2856839_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:spoIVFB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27970]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rplU]]'', ''[[spoIVFA]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27970 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27970 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:spoIVFB_context.gif]]