SpoIVFA - Revision history

Jstuelk at 12:46, 10 December 2014

2014-12-10T12:46:44Z

134.76.38.147 at 14:24, 2 April 2014

2014-04-02T14:24:02Z

Jstuelk: /* References */

2013-12-03T10:09:02Z

‎References

Jstuelk: /* Basic information/ Evolution */

2013-12-03T10:06:32Z

‎Basic information/ Evolution

Jstuelk at 10:03, 3 December 2013

2013-12-03T10:03:09Z

134.76.70.252 at 09:01, 12 November 2013

2013-11-12T09:01:47Z

Jstuelk at 17:51, 3 September 2013

2013-09-03T17:51:42Z

Jstuelk at 17:49, 3 September 2013

2013-09-03T17:49:17Z

134.76.70.252 at 14:09, 16 May 2013

2013-05-16T14:09:40Z

134.76.70.252 at 10:53, 14 May 2013

2013-05-14T10:53:39Z

← Older revision		Revision as of 12:46, 10 December 2014
Line 1:		Line 1:
−	* '''Description:~~''' inhibitor of [[SpoIVFB]] metalloprotease <br/><br/>~~	+	{{#bank: SpoIVFA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''spoIVFA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''bofB, spoVL ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| inhibitor of [[SpoIVFB]] metalloprotease~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| control of [[SigK]] activation~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27980 spoIVFA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SpoIVFA SpoIVFA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 29 kDa, 7.292~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 792 bp, 264 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[spoIVFB]]'', ''[[minD]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27980 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27980 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27980 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:spoIVFA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFA_2856832_2857626_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:spoIVFA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27980]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[sigma factors and their control]]}},~~
−	~~{{SubtiWiki category\|[[sporulation proteins]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[SigE regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU27980
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27980&redirect=T BSU27980]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIVFAB.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10331]
−
−	~~=== Additional information===~~
−
−
−
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:'''
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−	** the ectodomain of [[SpoIVFA]] is cleaved off by [[SpoIVB]] (first cleavage) {{PubMed\|24243021}}
−	** the domains that inhibits [[SpoIVFB]] is cleaved off by [[CtpB]] (second cleavage) {{PubMed\|24243021}}
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[SpoIVFB]]-[[SpoIVFA]], to facilitate the recruitment of [[BofA]] to [[SpoIVFB]] {{PubMed\|11959848}}
−	** [[BofA]]-[[SpoIVFA]] {{PubMed\|11959848}}
−	** [[SpoIVB]]-[[SpoIVFA]] {{PubMed\|24243021}}
−	** [[CtpB]]-[[SpoIVFA]] {{PubMed\|24243021}}
−
−	* '''[[Localization]]:'''
−	** mother cell membrane {{PubMed\|24243021}}
−	** integral membrane protein {{PubMed\|11959848}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27980&redirect=T BSU27980]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P26936 P26936]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27980]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−	** the ectodomain of [[SpoIVFA]] is cleaved off by [[SpoIVB]] (first cleavage) {{PubMed\|24243021}}
−	** the domains that inhibits [[SpoIVFB]] is cleaved off by [[CtpB]] (second cleavage) {{PubMed\|24243021}
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[spoIVFA]]-[[spoIVFB]]'' {{PubMed\|1942049}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFA_2856832_2857626_-1 spoIVFA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigE]] {{PubMed\|15699190,1942049}}
−
−	* '''Regulation:'''
−	** expressed early during sporulation in the mother cell ([[SigE]], [[SpoIIID]]) {{PubMed\|15699190,1942049,15383836}}
−
−	* '''Regulatory mechanism:'''
−	** [[SpoIIID]]: transcription repression {{PubMed\|15383836}}
−
−	* '''Additional information:'''
−	** the ectodomain of [[SpoIVFA]] is cleaved off by [[SpoIVB]] (first cleavage) {{PubMed\|24243021}}
−	** the domains that inhibits [[SpoIVFB]] is cleaved off by [[CtpB]] (second cleavage) {{PubMed\|24243021}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−
−	~~<pubmed>11959848,9501233,1577688,15292188,2115401,12940997,9078383,15752199 , 16818230 15699190,1942049,15383836 17557826 24243021 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 56: / Line 56: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIVFAB.html]
@@ Line 101: / Line 102: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 152: / Line 152: @@
 =References=
-<pubmed>11959848,9501233,1577688,15292188,2115401,12940997,9078383,15752199 , 16818230 15699190,1942049,15383836 17557826 </pubmed>
+<pubmed>11959848,9501233,1577688,15292188,2115401,12940997,9078383,15752199 , 16818230 15699190,1942049,15383836 17557826 24243021 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 72: / Line 72: @@
 * '''Catalyzed reaction/ biological activity:'''
-* '''Protein family:''' PDZ protease {{PubMed|24243021}}
+* '''Protein family:'''
 * '''Paralogous protein(s):'''

@@ Line 72: / Line 72: @@
 * '''Catalyzed reaction/ biological activity:'''
-* '''Protein family:'''
+* '''Protein family:''' PDZ protease {{PubMed|24243021}}
 * '''Paralogous protein(s):'''
@@ Line 81: / Line 81: @@
 * '''Domains:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 91: / Line 93: @@
 ** [[SpoIVFB]]-[[SpoIVFA]], to facilitate the recruitment of [[BofA]] to [[SpoIVFB]] {{PubMed|11959848}}
 ** [[BofA]]-[[SpoIVFA]] {{PubMed|11959848}}
 * '''[[Localization]]:'''
-** forespore outer membrane (according to Swiss-Prot)
+** mother cell membrane {{PubMed|24243021}}
 ** integral membrane protein {{PubMed|11959848}}
@@ Line 107: / Line 111: @@
 === Additional information===
+** the ectodomain of [[SpoIVFA]] is cleaved off by [[SpoIVB]] (first cleavage) {{PubMed|24243021}}
-cleaved by [[SpoIVB]] and [[CtpB]] {{PubMed|17557826}}
+** the domains that inhibits [[SpoIVFB]] is cleaved off by [[CtpB]] (second cleavage) {{PubMed|24243021}
 =Expression and regulation=
@@ Line 124: / Line 128: @@
 ** [[SpoIIID]]: transcription repression {{PubMed|15383836}}
-* '''Additional information:''' cleaved by [[SpoIVB]] and [[CtpB]]
+* '''Additional information:'''
 =Biological materials =

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27980 spoIVFA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIVFA SpoIVFA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SpoIVFA SpoIVFA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 7.292

@@ Line 35: / Line 35: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 91: / Line 87: @@
 * '''[[SubtInteract|Interactions]]:'''
 * '''[[Localization]]:'''
 ** forespore outer membrane (according to Swiss-Prot)
 === Database entries ===
@@ Line 115: / Line 113: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFA_2856832_2857626_-1 spoIVFA] {{PubMed|22383849}}
-* '''Sigma factor:''' [[SigE]] {{PubMed|15699190,1942049}}
+* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190,1942049}}
 * '''Regulation:'''

@@ Line 27: / Line 27: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFA_2856832_2857626_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:spoIVFA_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVFA_2856832_2857626_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:spoIVFA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27980]]
 |-
 |}

@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIVFB]]'', ''[[minD]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27980 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27980 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27980 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27980 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27980 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27980 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:spoIVFA_context.gif]]