SigA - Revision history

Jstuelk: /* Categories containing this gene/protein */

2014-10-27T16:40:23Z

‎Categories containing this gene/protein

Jstuelk: /* Extended information on the protein */

2014-10-27T16:40:04Z

‎Extended information on the protein

Jstuelk: /* References */

2014-08-13T10:47:45Z

‎References

Jstuelk at 10:46, 13 August 2014

2014-08-13T10:46:47Z

134.76.70.252 at 14:14, 17 April 2014

2014-04-17T14:14:33Z

134.76.70.252 at 09:37, 17 April 2014

2014-04-17T09:37:24Z

134.76.38.147 at 14:14, 2 April 2014

2014-04-02T14:14:42Z

Jstuelk: /* Reviews */

2013-12-13T17:20:08Z

‎Reviews

134.76.70.252 at 08:52, 12 November 2013

2013-11-12T08:52:59Z

Jstuelk at 12:04, 25 July 2013

2013-07-25T12:04:41Z

← Older revision		Revision as of 16:40, 27 October 2014
Line 1:		Line 1:
−	* '''Description:~~''' [[RNA polymerase]] major [[sigma factor]]~~ SigA ~~<br/><br/>~~	+	{{#bank: SigA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''sigA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''rpoD, crsA ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| [[RNA polymerase]] major [[sigma factor]] SigA~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| [[transcription]]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25200 sigA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigA SigA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 42 kDa, 4.634~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1113 bp, 371 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[cccA]]'', ''[[dnaG]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25200 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25200 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25200 DNA_with_flanks]
−	\|-
−	\|-
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:sigA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigA_2600214_2601329_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:sigA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25200]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[transcription]]}},~~
−	~~{{SubtiWiki category\|[[sigma factors and their control]]}},~~
−	~~{{SubtiWiki category\|[[essential genes]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[SigD regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[SigH regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU25200
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25200&redirect=T BSU25200]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yqxD-dnaG-sigA.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10314]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''[[Genes controlled by SigA\|List of SigA controlled genes]]'''
−
−	* '''Protein family:''' sigma-70 factor family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[Spo0A]]-[[SigA]] {{PubMed\|14976210}}
−	** [[SigA]]-([[RpoB]]-[[RpoC]]) {{PubMed\|19680289,19735077}}
−	** [[BsrA]]-[[SigA]]-[[RNA polymerase]]
−	** [[BsrB]]-[[SigA]]-[[RNA polymerase]]
−
−	* '''[[Localization]]:'''
−	** cytoplasm {{PubMed\|25313396}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25200&redirect=T BSU25200]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P06224 P06224]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU25200]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−	* '''Operon:'''
−	** ''[[yqxD]]-[[dnaG]]-[[sigA]]'' {{PubMed\|3298998}}
−	** ''[[sigA]]'' {{PubMed\|3919021}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigA_2600214_2601329_-1 sigA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−	** ''[[yqxD]]'': [[SigA]] {{PubMed\|3298998}}, [[SigH]] {{PubMed\|3127379}}
−	** ''[[sigA]]'': [[SigD]] {{PubMed\|3919021}}
−
−	* '''Regulation:'''
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−	** An [[ncRNA\|antisense RNA]] is predicted for ''[[sigA]]'' {{PubMed\|20525796}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 802 {{PubMed\|24696501}}
−	** number of protein molecules per cell (complex medium with amino acids, without glucose): 1811 {{PubMed\|24696501}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 1136 {{PubMed\|21395229}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 2062 {{PubMed\|21395229}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 1407 {{PubMed\|21395229}}
−
−	~~=Biological materials =~~
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	* [[Charles Moran]], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 22210308 24308327 </pubmed>~~
−
−	~~==Original publications==~~
−	<pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 25112476</pubmed>
−	~~[[Category:Protein-coding genes]]~~

@@ Line 100: / Line 100: @@
 ** [[BsrB]]-[[SigA]]-[[RNA polymerase]]
-* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
+* '''[[Localization]]:'''
 === Database entries ===

@@ Line 162: / Line 162: @@
 ==Original publications==
-<pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 25112476 </pubmed>
+<pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 25112476</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 162: / Line 162: @@
 ==Original publications==
-<pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 </pubmed>
+<pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 25112476 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 134: / Line 134: @@
 ** number of protein molecules per cell (minimal medium with glucose and ammonium): 802 {{PubMed|24696501}}
 ** number of protein molecules per cell (complex medium with amino acids, without glucose): 1811 {{PubMed|24696501}}
 =Biological materials =
 * '''Mutant:'''

@@ Line 132: / Line 132: @@
 * '''Additional information:'''
 ** An [[ncRNA|antisense RNA]] is predicted for ''[[sigA]]'' {{PubMed|20525796}}
 =Biological materials =

@@ Line 62: / Line 62: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yqxD-dnaG-sigA.html]
@@ Line 102: / Line 103: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 153: / Line 153: @@
 =References=
 ==Reviews==
-<pubmed> 22210308 </pubmed>
+<pubmed> 22210308 24308327 </pubmed>
 ==Original publications==
 <pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25200 sigA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SigA SigA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigA SigA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.634

@@ Line 39: / Line 39: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 120: / Line 120: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigA_2600214_2601329_-1 sigA] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 ** ''[[yqxD]]'': [[SigA]] {{PubMed|3298998}}, [[SigH]] {{PubMed|3127379}}
 ** ''[[sigA]]'': [[SigD]] {{PubMed|3919021}}
@@ Line 155: / Line 155: @@
 <pubmed> 22210308 </pubmed>
 ==Original publications==
-'''Additional publications:''' {{PubMed|22333917,20935043,20817769}}
+<pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 </pubmed>
 [[Category:Protein-coding genes]]