Scr - Revision history

Jstuelk at 12:34, 18 November 2014

2014-11-18T12:34:20Z

Jstuelk at 15:22, 4 October 2014

2014-10-04T15:22:49Z

Jstuelk: /* References */

2014-09-19T10:38:10Z

‎References

134.76.38.147 at 12:45, 2 April 2014

2014-04-02T12:45:16Z

134.76.70.252 at 14:56, 11 November 2013

2013-11-11T14:56:07Z

Jstuelk: /* Categories containing this gene/protein */

2012-04-03T15:42:08Z

‎Categories containing this gene/protein

Jstuelk at 15:40, 3 April 2012

2012-04-03T15:40:53Z

Jstuelk at 17:48, 30 November 2011

2011-11-30T17:48:59Z

Jstuelk at 17:55, 30 July 2011

2011-07-30T17:55:30Z

Lflorez at 13:53, 8 December 2010

2010-12-08T13:53:58Z

← Older revision		Revision as of 12:34, 18 November 2014
Line 1:		Line 1:
−	* '''Description:~~''' 4.5 S RNA<br/><br/>~~	+	{{#bank: Scr}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''scr''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| yes~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| small cytoplasmic RNA (scRNA, 4.5S RNA),~~
−
−	~~[[signal recognition particle]]-like ([[SRP]]) component~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| presecretory protein translocation~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this RNA in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=Scr Scr]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yaaJ]]'', ''[[dnaX]]''~~
−	\|-
−	~~\|style="background:#FAF8CC;" align="center"\|'''[http://subtiwiki.uni-goettingen.de/scr_nucleotide.txt Gene sequence (+200bp) ]'''~~
−	~~\|style="background:#FAF8CC;" align="center"\|'''[http://subtiwiki.uni-goettingen.de/scr_protein.txt Protein sequence]'''~~
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:scr_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|}
−
−	~~__TOC__~~
−
−	~~<br/><br/><br/><br/><br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[protein secretion]]}},~~
−	~~{{SubtiWiki category\|[[essential genes]]}},~~
−	~~{{SubtiWiki category\|[[ncRNA]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:'''
−
−	~~===Phenotypes of a mutant ===~~
−	* the gene is essential {{PubMed\|7506707}}
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU_MISC_RNA_2&redirect=T BSU_misc_RNA_2]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG00095]
−
−	* '''Structure:'''
−
−	~~=== Additional information===~~
−
−
−	~~=The RNA=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	~~=== Extended information on the RNA===~~
−
−	* '''Kinetic information'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[Scr]]-[[Ffh]] in the [[signal recognition particle]]
−
−	* '''[[Localization]]'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU_MISC_RNA_2&redirect=T BSU_misc_RNA_2]
−
−	* '''Structure''': [http://www.rcsb.org/pdb/explore.do?structureId=4WFL 4WFL] {{PubMed\|25270875}}
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[yaaJ]]-[[scr]], [[scr]]''
−
−	* '''Sigma factor:''' [[SigA]] (both promoters)
−
−	* '''Regulation:'''
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:''' transcribed as 354 nt precursor, cleaved at the 5' end by [[rnc\| RNase III]] and at the 3' site by [[rnjA\| RNase J1]] to yield a 275 nt molecule, final trimming to 271 nt sc RNA by [[rph\| RNase PH]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17576666 PubMed]
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	[[David Bechhofer]], Mount Sinai School, New York, USA [http://www.mountsinai.org/Research/Centers%20Laboratories%20and%20Programs/Bechhofer%20Laboratory?citype=Physician&ciid=Bechhofer%20David%20H%201255565 Homepage]
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~== Reviews ==~~
−	~~<pubmed> 25212246 </pubmed>~~
−	~~== Original publications ==~~
−	~~<pubmed>9346318,2468993,17576666, 1372600,7506707 1383945 7538759 10224127 9677377 8662730 10222262 25270875 </pubmed>~~
−
−	~~[[Category:small RNA]]~~

@@ Line 78: / Line 78: @@
 * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU_MISC_RNA_2&redirect=T BSU_misc_RNA_2]
-* '''Structure''':
+* '''Structure''': [http://www.rcsb.org/pdb/explore.do?structureId=4WFL 4WFL] {{PubMed|25270875}}
 === Additional information===
@@ Line 112: / Line 112: @@
 <pubmed> 25212246 </pubmed>
 == Original publications ==
-<pubmed>9346318,2468993,17576666, 1372600,7506707 1383945 7538759 10224127 9677377 8662730 10222262</pubmed>
+<pubmed>9346318,2468993,17576666, 1372600,7506707 1383945 7538759 10224127 9677377 8662730 10222262 25270875 </pubmed>
 [[Category:small RNA]]

@@ Line 109: / Line 109: @@
 =References=
+== Reviews ==
 <pubmed>9346318,2468993,17576666, 1372600,7506707 1383945 7538759 10224127 9677377 8662730 10222262</pubmed>
 [[Category:small RNA]]

@@ Line 49: / Line 49: @@
 * the gene is essential {{PubMed|7506707}}
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 75: / Line 76: @@
 === Database entries ===
 * '''Structure''':

@@ Line 16: / Line 16: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || presecretory protein translocation
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this RNA in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Scr Scr]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this RNA in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=Scr Scr]
 |-
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yaaJ]]'', ''[[dnaX]]''

@@ Line 34: / Line 34: @@
 = [[Categories]] containing this gene/protein =
 {{SubtiWiki category|[[protein secretion]]}},
 {{SubtiWiki category|[[ncRNA]]}}

@@ Line 8: / Line 8: @@
 |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 |-
-|style="background:#ABCDEF;" align="center"| '''Essential''' || no
+|style="background:#ABCDEF;" align="center"| '''Essential''' || yes
 |-
 |style="background:#ABCDEF;" align="center"| '''Product''' || small cytoplasmic RNA (scRNA, 4.5S RNA),
@@ Line 46: / Line 46: @@
 ===Phenotypes of a mutant ===
+* the gene is essential {{PubMed|7506707}}
 === Database entries ===
@@ Line 107: / Line 107: @@
 =References=
-<pubmed>9346318,2468993,17576666, </pubmed>
+<pubmed>9346318,2468993,17576666, 1372600,7506707 1383945 7538759 10224127 9677377 8662730 10222262</pubmed>
 [[Category:small RNA]]

@@ Line 12: / Line 12: @@
 |style="background:#ABCDEF;" align="center"| '''Product''' || small cytoplasmic RNA (scRNA, 4.5S RNA),
-signal recognition particle-like (SRP) component
+[[signal recognition particle]]-like ([[SRP]]) component
 |-
 |style="background:#ABCDEF;" align="center"|'''Function''' || presecretory protein translocation
@@ Line 56: / Line 56: @@
 === Additional information===
@@ Line 69: / Line 68: @@
 * '''Kinetic information'''
-* '''Interactions:''' [[Scr]]-[[Ffh]]
+* '''[[SubtInteract|Interactions]]:'''
-* '''Localization'''
+* '''[[Localization]]'''
 === Database entries ===

@@ Line 29: / Line 29: @@
 <br/><br/><br/><br/><br/><br/>
 =The gene=
@@ Line 49: / Line 56: @@
-= Categories containing this gene/protein =
 =The RNA=