QcrA - Revision history

Jstuelk: /* Original publications */

2015-08-05T17:17:07Z

‎Original publications

134.76.70.252 at 09:53, 17 April 2014

2014-04-17T09:53:44Z

134.76.38.147 at 14:03, 2 April 2014

2014-04-02T14:03:22Z

Jstuelk at 09:17, 22 March 2014

2014-03-22T09:17:28Z

Jstuelk: /* Extended information on the protein */

2013-12-17T11:47:19Z

‎Extended information on the protein

Jstuelk: /* Extended information on the protein */

2013-12-17T11:45:58Z

‎Extended information on the protein

Jstuelk at 11:45, 17 December 2013

2013-12-17T11:45:15Z

Jstuelk at 14:22, 6 December 2013

2013-12-06T14:22:43Z

134.76.70.252 at 08:42, 12 November 2013

2013-11-12T08:42:51Z

Jstuelk at 18:07, 11 August 2013

2013-08-11T18:07:04Z

← Older revision		Revision as of 17:17, 5 August 2015
Line 1:		Line 1:
−	* '''Description:~~''' Rieske factor, menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc1 complex<br/><br/>~~	+	{{#bank: QcrA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''qcrA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''bfcA, petC ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit)~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| [[respiration]]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22560 qcrA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=QcrA QcrA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 18 kDa, 6.078~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 501 bp, 167 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[qcrB]]'', ''[[ypiF]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU22560 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU22560 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU22560 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:qcrA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=qcrA_2364589_2365092_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:qcrA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22560]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[respiration]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[AbrB regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[CcpA regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[ResD regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU22560
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22560&redirect=T BSU22560]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/qcrABC.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11325]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' accD/PCCB family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:''' contains an iron-sulfur cluster
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** part of a [[Respiratory complexes and supercomplexes\|respiratory supercomplex]] {{PubMed\|23880299}}
−	** [[QcrA]]-[[QcrB]]-[[QcrC]] {{PubMed\|23880299}}
−
−	* '''[[Localization]]:'''
−	** cell membrane {{PubMed\|23880299}}
−	** delivered to the membrane by the [[TatAY]]-[[TatCY]] [[protein secretion]] system, this depends on prior dusulfide bond formation and co-factor insertion {{PubMed\|24652282,23256564}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22560&redirect=T BSU22560]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P46911 P46911]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU22560]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−	* '''Operon:''' ''[[qcrA]]-[[qcrB]]-[[qcrC]]'' {{PubMed\|7592464}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=qcrA_2364589_2365092_-1 qcrA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigA]] {{PubMed\|7592464}}
−
−	* '''Regulation:'''
−	** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]
−	** induced by oxygen limitation ([[ResD]]) {{PubMed\|8631715}}
−	** repressed by glucose (5.5-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]
−
−	* '''Regulatory mechanism:'''
−	** [[ResD]]: transcription activation {{PubMed\|8631715}}
−	** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]
−	** [[AbrB]]: transcription repression {{PubMed\|20817675}}
−
−	* '''Additional information:'''
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 204 {{PubMed\|24696501}}
−	** number of protein molecules per cell (complex medium with amino acids, without glucose): 1343 {{PubMed\|24696501}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~== Reviews ==~~
−	~~<pubmed> 24140208 </pubmed>~~
−	~~== Original publications ==~~
−	~~<pubmed>8631715,7592464, 23880299,12850135 12107147, 20817675 23256564 24652282</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

← Older revision		Revision as of 09:53, 17 April 2014
Line 126:		Line 126:

	* '''Additional information:'''		* '''Additional information:'''
		+	** number of protein molecules per cell (minimal medium with glucose and ammonium): 204 {{PubMed\|24696501}}
		+	** number of protein molecules per cell (complex medium with amino acids, without glucose): 1343 {{PubMed\|24696501}}

	=Biological materials =		=Biological materials =

@@ Line 57: / Line 57: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/qcrABC.html]
@@ Line 95: / Line 96: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 1: / Line 1: @@
-* '''Description:''' menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc complex<br/><br/>
+* '''Description:''' Rieske factor, menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc1 complex<br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 63: / Line 63: @@
 === Additional information===
 =The protein=
@@ Line 95: / Line 92: @@
 * '''[[Localization]]:'''
 ** cell membrane {{PubMed|23880299}}
-** delivered to the membrane by the [[TatAY]]-[[TatCY]] [[protein secretion]] system {{PubMed|23256564}}
+** delivered to the membrane by the [[TatAY]]-[[TatCY]] [[protein secretion]] system, this depends on prior dusulfide bond formation and co-factor insertion {{PubMed|24652282,23256564}}
 === Database entries ===
@@ Line 150: / Line 147: @@
 <pubmed> 24140208 </pubmed>
 == Original publications ==
-<pubmed>8631715,7592464, 23880299,12850135 12107147, 20817675 23256564 </pubmed>
+<pubmed>8631715,7592464, 23880299,12850135 12107147, 20817675 23256564 24652282</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 95: / Line 95: @@
 * '''[[Localization]]:'''
 ** cell membrane {{PubMed|23880299}}
-** delivered to the membran by the [[TatAY]]-[[TatCY]] [[protein secretion]] system {{PubMed|23256564}}
+** delivered to the membrane by the [[TatAY]]-[[TatCY]] [[protein secretion]] system {{PubMed|23256564}}
 === Database entries ===

@@ Line 81: / Line 81: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):''' contains an iron-sulfur cluster
+* '''[[Cofactors]]:''' contains an iron-sulfur cluster
 * '''Effectors of protein activity:'''
@@ Line 95: / Line 95: @@
 * '''[[Localization]]:'''
 ** cell membrane {{PubMed|23880299}}
 === Database entries ===
@@ Line 146: / Line 147: @@
 =References=
 <pubmed>8631715,7592464, 23880299,12850135 12107147, 20817675</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22560 qcrA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/QcrA QcrA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=QcrA QcrA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 6.078