PksC - Revision history

134.76.70.252 at 14:11, 17 April 2014

2014-04-17T14:11:53Z

134.76.70.252 at 10:01, 17 April 2014

2014-04-17T10:01:21Z

134.76.38.147 at 13:47, 2 April 2014

2014-04-02T13:47:39Z

Jstuelk: /* This gene is a member of the following regulons */

2013-12-18T17:54:07Z

‎This gene is a member of the following regulons

Jstuelk: /* Expression and regulation */

2013-12-18T17:39:20Z

‎Expression and regulation

Jstuelk: /* Expression and regulation */

2013-12-17T16:18:28Z

‎Expression and regulation

Jstuelk: /* Expression and regulation */

2013-12-17T16:18:11Z

‎Expression and regulation

Jstuelk at 16:17, 17 December 2013

2013-12-17T16:17:36Z

134.76.70.252 at 13:26, 16 May 2013

2013-05-16T13:26:05Z

134.76.70.252 at 10:18, 14 May 2013

2013-05-14T10:18:02Z

← Older revision		Revision as of 14:11, 17 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' bacillaene synthase trans-acting acyltransferase <br/><br/>~~	+	{{#bank: PksC}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''pksC''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| bacillaene synthase trans-acting acyltransferase~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| polyketide (bacillaene) synthesis~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17100 pksC]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 32 kDa, 5.328~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 864 bp, 288 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[pksB]]'', ''[[pksD]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17100 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:pksC_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:pksC_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17100]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[miscellaneous metabolic pathways]]}},~~
−	~~{{SubtiWiki category\|[[biosynthesis of antibacterial compounds]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[AbrB regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[CodY regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU17100
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17100&redirect=T BSU17100]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12649]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:'''
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17100&redirect=T BSU17100]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/O34825 O34825]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU17100]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[pksC]]-[[pksD]]-[[pksE]]-[[acpK]]-[[pksF]]-[[pksG]]-[[pksH]]-[[pksI]]-[[pksJ]]-[[pksL]]-[[pksM]]-[[pksN]]-[[pksR]]'' {{PubMed\|22383849}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 pksC] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−	** expressed during the transition from growth to stationary phase ([[AbrB]], [[CodY]]) {{PubMed\|24187085}}
−
−	* '''Regulatory mechanism:'''
−	** [[AbrB]]: transcription repression {{PubMed\|24187085}}
−	** [[CodY]]: transcription activation {{PubMed\|24187085}}
−
−	* '''Additional information:'''
−	** this is a very large operon comprising about 75 kb
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 100 {{PubMed\|24696501}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~<pubmed>22383849 21505242 24187085</pubmed>~~
−	~~[[Category:Protein-coding genes]]~~

@@ Line 118: / Line 118: @@
 * '''Additional information:'''
 ** this is a very large operon comprising about 75 kb
 =Biological materials =

@@ Line 54: / Line 54: @@
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 88: / Line 89: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 42: / Line 42: @@
 = This gene is a member of the following [[regulons]] =
+{{SubtiWiki regulon|[[AbrB regulon]]}},
 =The gene=

@@ Line 111: / Line 111: @@
 * '''Regulatory mechanism:'''
 ** [[AbrB]]: transcription repression {{PubMed|24187085}}
 * '''Additional information:'''

@@ Line 100: / Line 100: @@
 =Expression and regulation=
-* '''Operon:''' [[pksC]]-[[pksD]]-[[pksE]]-[[acpK]]-[[pksF]]-[[pksG]]-[[pksH]]-[[pksI]]-[[pksJ]]-[[pksL]]-[[pksM]]-[[pksN]]-[[pksR]] {{PubMed|22383849}}
+* '''Operon:''' ''[[pksC]]-[[pksD]]-[[pksE]]-[[acpK]]-[[pksF]]-[[pksG]]-[[pksH]]-[[pksI]]-[[pksJ]]-[[pksL]]-[[pksM]]-[[pksN]]-[[pksR]]'' {{PubMed|22383849}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 pksC] {{PubMed|22383849}}

@@ Line 35: / Line 35: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 78: / Line 74: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 104: / Line 100: @@
 =Expression and regulation=
-* '''Operon:'''
+* '''Operon:''' [[pksC]]-[[pksD]]-[[pksE]]-[[acpK]]-[[pksF]]-[[pksG]]-[[pksH]]-[[pksI]]-[[pskJ]]-[[pksL]]-[[pksM]]-[[pksN]]-[[pksR]] {{PubMed|22383849}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 pksC] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''
 * '''Regulatory mechanism:'''
 * '''Additional information:'''
 =Biological materials =
@@ Line 135: / Line 134: @@
 =References=
-'''Additional publications:''' {{PubMed|21505242}}
+<pubmed>22383849 21505242 24187085</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 27: / Line 27: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:pksC_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksC_1783763_1784629_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:pksC_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17100]]
 |-
 |}

@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pksB]]'', ''[[pksD]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17100 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17100 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:pksC_context.gif]]