ParA - Revision history

Jstuelk: /* Reviews */

2015-08-20T12:51:29Z

‎Reviews

Jstuelk: /* Original publications */

2015-08-10T08:32:28Z

‎Original publications

Jstuelk at 08:06, 10 August 2015

2015-08-10T08:06:17Z

Jstuelk: Jstuelk moved page Soj to ParA: 16677298

2015-08-10T08:00:48Z

Jstuelk moved page Soj to ParA: 16677298

Jstuelk: /* Expression and regulation */

2015-01-13T10:15:12Z

‎Expression and regulation

134.76.70.252 at 09:45, 17 April 2014

2014-04-17T09:45:23Z

134.76.38.147 at 15:18, 2 April 2014

2014-04-02T15:18:53Z

Jstuelk at 15:12, 16 February 2014

2014-02-16T15:12:42Z

134.76.70.252 at 09:49, 12 November 2013

2013-11-12T09:49:42Z

Hmurray: /* Labs working on this gene/protein */

2013-08-15T09:12:27Z

‎Labs working on this gene/protein

← Older revision		Revision as of 12:51, 20 August 2015
Line 1:		Line 1:
−	* '''Description:~~''' ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of [[sporulation]] initiation <br/><br/>~~	+	{{#bank: ParA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''parA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''soj, spo0JA ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| negative regulator of [[sporulation]] initiation~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| forespore chromosome partitioning /<br/> negative regulation of [[sporulation]] initiation~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40970 parA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ParA ParA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 27 kDa, 4.903~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 759 bp, 253 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[parB]]'', ''[[yyaB]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU40970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU40970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU40970 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:soj_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=parA_4206397_4207158_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:soj_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40970]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[DNA condensation/ segregation]]}},~~
−	~~{{SubtiWiki category\|[[sporulation/ other]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[Spo0A regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU40970
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40970&redirect=T BSU40970]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/soj-spo0J.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10055]
−
−	~~=== Additional information===~~
−
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:''' regulates [[DNA replication]] initiation by either inhibiting or activating the [[DNA replication]] initiator protein [[DnaA]] {{PubMed\|21235642}}; regulation of ''Spo0A'' expression {{PubMed\|10852876}}
−
−	* '''Protein family:''' parA family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−	** [[ParB]] inhibits [[ParA]] dimerization and concomitant DNA-binding activity by stimulating [[ParA]] ATPase activity {{PubMed\|21235642}}
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[ParA]]-[[ParB]] {{PubMed\|21235642}}
−	** [[ParA]]-[[DnaA]] {{PubMed\|22286949}}
−
−	* '''[[Localization]]:'''
−	** polar/ septal at the cell membrane {{PubMed\|20566861}}
−	** polar localization depends on the proton motive force {{PubMed\|20566861}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40970&redirect=T BSU40970]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P37522 P37522]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU40970]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−	* '''Operon:''' ''[[parA]]-[[parB]]'' {{PubMed\|22383849}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=parA_4206397_4207158_-1 parA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−	** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed]
−
−	* '''Regulatory mechanism:'''
−	** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed]
−
−	* '''Additional information:'''
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 84 {{PubMed\|24696501}}
−	** number of protein molecules per cell (complex medium with amino acids, without glucose): 280 {{PubMed\|24696501}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−	* [[Heath Murray]], Centre for Bacterial Cell Biology, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/heath.murray homepage]
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 20157337 22934648 </pubmed>~~
−	~~== Original publications ==~~
−	~~<pubmed>15659156,11532141,19450516,18854156,10619015,8866474,12492861,9701805,12950914,14651647, 19450516 20566861 21235642 10852876 14563866 26253537 22286949 21911367</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 149: / Line 149: @@
 <pubmed> 20157337 22934648 </pubmed>
 == Original publications ==
-<pubmed>15659156,11532141,19450516,18854156,10619015,8866474,12492861,9701805,12950914,14651647, 19450516 20566861 21235642 10852876 14563866 22286949 21911367</pubmed>
+<pubmed>15659156,11532141,19450516,18854156,10619015,8866474,12492861,9701805,12950914,14651647, 19450516 20566861 21235642 10852876 14563866 26253537 22286949 21911367</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 1: / Line 1: @@
-* '''Description:''' ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation <br/><br/>
+* '''Description:''' ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of [[sporulation]] initiation <br/><br/>
 {| align="right" border="1" cellpadding="2"
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''soj''
+|''parA''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''parA, spo0JA ''
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''soj, spo0JA ''
 |-
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || negative regulator of sporulation initiation
+|style="background:#ABCDEF;" align="center"| '''Product''' || negative regulator of [[sporulation]] initiation
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || forespore chromosome partitioning /<br/> negative regulation of sporulation initiation
+|style="background:#ABCDEF;" align="center"|'''Function''' || forespore chromosome partitioning /<br/> negative regulation of [[sporulation]] initiation
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40970 soj]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40970 parA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=Soj Soj]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ParA ParA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 4.903
@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 759 bp, 253 aa
 |-
-|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spo0J]]'', ''[[yyaB]]''
+|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[parB]]'', ''[[yyaB]]''
 |-
 |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU40970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU40970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU40970 DNA_with_flanks]
@@ Line 86: / Line 86: @@
 * '''Effectors of protein activity:'''
-** [[Spo0J]] inhibits [[Soj]] dimerization and concomitant DNA-binding activity by stimulating Soj ATPase activity {{PubMed|21235642}}
+** [[ParB]] inhibits [[ParA]] dimerization and concomitant DNA-binding activity by stimulating [[ParA]] ATPase activity {{PubMed|21235642}}
 * '''[[SubtInteract|Interactions]]:'''
-** [[Spo0J]]-[[Soj]] {{PubMed|21235642}}
+** [[ParA]]-[[ParB]] {{PubMed|21235642}}
-** [[Soj]]-[[DnaA]] {{PubMed|22286949}}
+** [[ParA]]-[[DnaA]] {{PubMed|22286949}}
 * '''[[Localization]]:'''
@@ Line 110: / Line 110: @@
 =Expression and regulation=
-* '''Operon:''' ''[[soj]]-[[spo0J]]'' {{PubMed|22383849}}
+* '''Operon:''' ''[[parA]]-[[parB]]'' {{PubMed|22383849}}
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=parA_4206397_4207158_-1 soj] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=parA_4206397_4207158_-1 parA] {{PubMed|22383849}}
 * '''[[Sigma factor]]:'''

@@ Line 110: / Line 110: @@
 =Expression and regulation=
-* '''Operon:''' ''[[soj]]-[[spo0J]]'' (according to [http://dbtbs.hgc.jp/COG/prom/soj-spo0J.html DBTBS])
+* '''Operon:''' ''[[soj]]-[[spo0J]]'' {{PubMed|22383849}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=parA_4206397_4207158_-1 soj] {{PubMed|22383849}}

← Older revision		Revision as of 09:45, 17 April 2014
Line 123:		Line 123:

	* '''Additional information:'''		* '''Additional information:'''
		+	** number of protein molecules per cell (minimal medium with glucose and ammonium): 84 {{PubMed\|24696501}}
		+	** number of protein molecules per cell (complex medium with amino acids, without glucose): 280 {{PubMed\|24696501}}

	=Biological materials =		=Biological materials =

← Older revision	Revision as of 08:00, 10 August 2015
(No difference)

@@ Line 56: / Line 56: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/soj-spo0J.html]
@@ Line 96: / Line 97: @@
 === Database entries ===
 * '''Structure:'''

← Older revision		Revision as of 09:12, 15 August 2013
Line 137:		Line 137:

	=Labs working on this gene/protein=		=Labs working on this gene/protein=
		+	* [[Heath Murray]], Centre for Bacterial Cell Biology, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/heath.murray homepage]

	=Your additional remarks=		=Your additional remarks=