OpuAA - Revision history

134.76.70.252 at 09:32, 17 April 2014

2014-04-17T09:32:23Z

134.76.38.147 at 12:56, 2 April 2014

2014-04-02T12:56:07Z

Jstuelk at 14:48, 26 February 2014

2014-02-26T14:48:47Z

134.76.70.252 at 10:06, 7 January 2014

2014-01-07T10:06:40Z

134.76.70.252 at 15:08, 11 November 2013

2013-11-11T15:08:53Z

Jstuelk at 15:12, 24 May 2013

2013-05-24T15:12:36Z

134.76.70.252 at 12:29, 16 May 2013

2013-05-16T12:29:49Z

134.76.70.252 at 09:25, 14 May 2013

2013-05-14T09:25:28Z

134.76.70.252 at 12:05, 13 May 2013

2013-05-13T12:05:44Z

Jstuelk at 10:23, 26 November 2012

2012-11-26T10:23:25Z

← Older revision		Revision as of 09:32, 17 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' glycine betaine [[ABC transporter]] (ATP-binding protein) <br/><br/>~~	+	{{#bank: OpuAA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''opuAA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| glycine betaine [[ABC transporter]] (ATP-binding protein)~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| compatible solute transport~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02980 opuAA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=OpuAA OpuAA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=opuAA opuAA]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 46 kDa, 5.107~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1254 bp, 418 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yceK]]'', ''[[opuAB]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02980 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02980 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02980 DNA_with_flanks]
−	\|-
−	\|-
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:opuAA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=opuAA_321013_322269_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:opuAA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02980]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[ABC transporters]]}},~~
−	~~{{SubtiWiki category\|[[coping with hyper-osmotic stress]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[RemA regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU02980
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02980&redirect=T BSU02980]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11370]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−	** uptake of glycine betaine
−	** uptake of dimethylglycine {{PubMed\|24561588}}
−
−	* '''Protein family:''' [[ABC transporter]] domain (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[OpuAA]]-[[OpuAB]]-[[OpuAC]] {{PubMed\|10092453}}
−
−	* '''[[Localization]]:''' associated to the membrane (via [[OpuAB]]) {{PubMed\|10092453}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02980&redirect=T BSU02980]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P46920 P46920]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU02980]
−
−	* '''E.C. number:''' [http://www.expasy.org/enzyme/3.6.3.32 3.6.3.32]
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[opuAA]]-[[opuAB]]-[[opuAC]]'' {{PubMed\|22383849}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=opuAA_321013_322269_1 opuAA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigA]] {{PubMed\|23175650}}
−
−	* '''Regulation:'''
−	** induced by osmotic stress {{PubMed\|23175650}}
−	** repressed by intracellular glycine betaine {{PubMed\|23175650}}
−
−	* '''Regulatory mechanism:'''
−	** [[RemA]]: transcription activation {{PubMed\|23646920}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~[[Erhard Bremer]], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−
−	~~<pubmed>7622480,10092453,16645306,14623183,18321243,16225868, 21296969 22383849 23175650 23646920 24561588</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 60: / Line 60: @@
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 97: / Line 98: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 66: / Line 66: @@
 === Additional information===
 =The protein=
@@ Line 72: / Line 71: @@
 === Basic information/ Evolution ===
-* '''Catalyzed reaction/ biological activity:''' ATP + H<sub>2</sub>O + quaternary amine(Out) = ADP + phosphate + quaternary amine(In) (according to Swiss-Prot)
+* '''Catalyzed reaction/ biological activity:'''
 * '''Protein family:''' [[ABC transporter]] domain (according to Swiss-Prot)
@@ Line 82: / Line 83: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 146: / Line 147: @@
 =References=
-<pubmed>7622480,10092453,16645306,14623183,18321243,16225868, 21296969 22383849 23175650 23646920</pubmed>
+<pubmed>7622480,10092453,16645306,14623183,18321243,16225868, 21296969 22383849 23175650 23646920 24561588</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 18: / Line 18: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=OpuAA OpuAA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=opuAA opuAA]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 5.107

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02980 opuAA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/OpuAA OpuAA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=OpuAA OpuAA]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''

@@ Line 49: / Line 49: @@
 = This gene is a member of the following [[regulons]] =
+{{SubtiWiki regulon|[[RemA regulon]]}}
 =The gene=
@@ Line 120: / Line 120: @@
 * '''Regulatory mechanism:'''
 * '''Additional information:'''
@@ Line 145: / Line 146: @@
 =References=
-<pubmed>7622480,10092453,16645306,14623183,18321243,16225868, 21296969 22383849 23175650</pubmed>
+<pubmed>7622480,10092453,16645306,14623183,18321243,16225868, 21296969 22383849 23175650 23646920</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 33: / Line 33: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=opuAA_321013_322269_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:opuAA_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=opuAA_321013_322269_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:opuAA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02980]]
 |-
 |}

@@ Line 26: / Line 26: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yceK]]'', ''[[opuAB]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02980 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02980 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02980 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02980 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02980 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02980 DNA_with_flanks]
 |-
 |-

@@ Line 41: / Line 41: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 70: / Line 66: @@
 === Additional information===
@@ Line 115: / Line 109: @@
 =Expression and regulation=
-* '''Operon:'''
+* '''Operon:''' ''[[opuAA]]-[[opuAB]]-[[opuAC]]'' {{PubMed|22383849}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=opuAA_321013_322269_1 opuAA] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:''' [[SigA]]  {{PubMed|23175650}}
 * '''Regulation:'''
 * '''Regulatory mechanism:'''
@@ Line 149: / Line 145: @@
 =References=
-<pubmed>7622480,10092453,16645306,14623183,18321243,16225868, 21296969 </pubmed>
+<pubmed>7622480,10092453,16645306,14623183,18321243,16225868, 21296969 22383849 23175650</pubmed>
 [[Category:Protein-coding genes]]