MurJ - Revision history

Jstuelk: /* Phenotypes of a mutant */

2015-05-08T12:59:48Z

‎Phenotypes of a mutant

Jstuelk: /* Categories containing this gene/protein */

2015-05-08T12:49:42Z

‎Categories containing this gene/protein

Jstuelk: /* Basic information/ Evolution */

2015-05-08T11:22:58Z

‎Basic information/ Evolution

Jstuelk at 10:57, 8 May 2015

2015-05-08T10:57:46Z

Jstuelk at 06:58, 30 April 2015

2015-04-30T06:58:28Z

Jstuelk: Jstuelk moved page YtgP to MurJ: 25918422

2015-04-30T06:50:34Z

Jstuelk moved page YtgP to MurJ: 25918422

134.76.38.147 at 14:32, 2 April 2014

2014-04-02T14:32:57Z

134.76.70.252 at 14:20, 16 May 2013

2013-05-16T14:20:40Z

134.76.70.252 at 11:03, 14 May 2013

2013-05-14T11:03:08Z

134.76.70.252 at 13:38, 13 May 2013

2013-05-13T13:38:24Z

← Older revision		Revision as of 12:59, 8 May 2015
Line 1:		Line 1:
−	* '''Description:~~''' lipid II flippase<br/><br/>~~	+	{{#bank: MurJ}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''murJ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''ytgP ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| lipid II flippase~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| export of lipid II~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30050 murJ]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 59 kDa, 10.089~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1632 bp, 544 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[ytzG]]'', ''[[ytfP]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30050 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:ytgP_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytgP_3073531_3075165_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:ytgP_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30050]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[cell wall synthesis]]}},~~
−	~~{{SubtiWiki category\|[[biosynthesis of cell wall components]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU30050
−
−	~~===Phenotypes of a mutant ===~~
−	* an ''[[amj]] [[murJ]]'' double mutant is not viable {{PubMed\|25918422}}
−	* mutants lacking [[MurJ]] produce long cells and chains of cells {{PubMed\|19648239}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30050&redirect=T BSU30050]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13856]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' [[MOP exporter family]]
−
−	* '''Paralogous protein(s):''' [[SpoVB]], [[YabM]], [[YkvU]]
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30050&redirect=T BSU30050]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/O34674 O34674]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU30050]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:'''
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytgP_3073531_3075165_-1 murJ] {{PubMed\|22383849}}
−
−	* '''Sigma factor:'''
−
−	* '''Regulation:'''
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~<pubmed> 19648239 19666716 25918422</pubmed>~~
−	~~[[Category:Protein-coding genes]]~~

@@ Line 39: / Line 39: @@
 = [[Categories]] containing this gene/protein =
 {{SubtiWiki category|[[cell wall synthesis]]}},
-{{SubtiWiki category|[[biosynthesis of cell wall components]]}}
+{{SubtiWiki category|[[biosynthesis of cell wall components]]}},
 = This gene is a member of the following [[regulons]] =

@@ Line 69: / Line 69: @@
 * '''Catalyzed reaction/ biological activity:'''
-* '''Protein family:'''
+* '''Protein family:''' [[MOP exporter family]]
 * '''Paralogous protein(s):''' [[SpoVB]], [[YabM]], [[YkvU]]

@@ Line 4: / Line 4: @@
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''ytgP''
+|''murJ''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytgP ''
 |-
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || export of lipid II
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30050 ytgP]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30050 murJ]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 59 kDa, 10.089
@@ Line 106: / Line 106: @@
 * '''Operon:'''
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytgP_3073531_3075165_-1 ytgP] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytgP_3073531_3075165_-1 murJ] {{PubMed|22383849}}
 * '''Sigma factor:'''

@@ Line 1: / Line 1: @@
-* '''Description:''' similar to spore cortex protein <br/><br/>
+* '''Description:''' lipid II flippase<br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 10: / Line 10: @@
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+|style="background:#ABCDEF;" align="center"| '''Product''' || lipid II flippase
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+|style="background:#ABCDEF;" align="center"|'''Function''' || export of lipid II
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30050 ytgP]
@@ Line 35: / Line 35: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 55: / Line 51: @@
 ===Phenotypes of a mutant ===
+* an ''[[amj]] [[murJ]]'' double mutant is not viable {{PubMed|25918422}}
-Mutants lacking YtgP produce long cells and chains of cells, suggesting a role in cell division.  {{PubMed|19648239}}
+* mutants lacking [[MurJ]] produce long cells and chains of cells  {{PubMed|19648239}}
 === Database entries ===
@@ Line 66: / Line 62: @@
 === Additional information===
 =The protein=
@@ Line 142: / Line 135: @@
 =References=
-<pubmed> 19648239 19666716 </pubmed>
+<pubmed> 19648239 19666716 25918422</pubmed>
 [[Category:Protein-coding genes]]

← Older revision	Revision as of 06:50, 30 April 2015
(No difference)

@@ Line 59: / Line 59: @@
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 96: / Line 97: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 27: / Line 27: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytgP_3073531_3075165_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ytgP_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytgP_3073531_3075165_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ytgP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30050]]
 |-
 |}

@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytzG]]'', ''[[ytfP]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30050 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30050 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:ytgP_context.gif]]