Mta - Revision history

Jstuelk at 13:18, 22 June 2014

2014-06-22T13:18:07Z

134.76.38.147 at 15:01, 2 April 2014

2014-04-02T15:01:14Z

134.76.70.252 at 14:47, 16 May 2013

2013-05-16T14:47:44Z

134.76.70.252 at 11:29, 14 May 2013

2013-05-14T11:29:25Z

134.76.70.252 at 14:04, 13 May 2013

2013-05-13T14:04:00Z

134.76.70.252 at 16:50, 7 August 2012

2012-08-07T16:50:11Z

134.76.70.252 at 10:59, 23 April 2012

2012-04-23T10:59:09Z

134.76.70.252 at 08:10, 17 April 2012

2012-04-17T08:10:48Z

Jstuelk: /* Extended information on the protein */

2011-12-02T18:10:24Z

‎Extended information on the protein

Jstuelk at 19:39, 18 December 2010

2010-12-18T19:39:50Z

← Older revision		Revision as of 13:18, 22 June 2014
Line 1:		Line 1:
−	* '''Description:~~''' transcriptional activator of multidrug-efflux transporter genes, activates ''[[ymfD]]'' expression <br/><br/>~~	+	{{#bank: Mta}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''mta''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''ywnD ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| transcriptional activator~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| regulation of multidrug-efflux transporter genes~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36600 mta]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 29 kDa, 4.949~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 771 bp, 257 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[clsA]]'', ''[[ywnC]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36600 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36600 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36600 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:mta_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mta_3764133_3764906_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:mta_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36600]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−
−
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[transcription factors and their control]]}},~~
−	~~{{SubtiWiki category\|[[resistance against toxins/ antibiotics]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[Mta regulon]]}}~~
−	~~=The [[Mta regulon]]=~~
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU36600
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU36600&redirect=T BSU36600]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mta.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12482]
−
−	~~=== Additional information===~~
−
−
−
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:'''
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU36600&redirect=T BSU36600]
−
−	* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1JBG 1JBG] (N-terminal domain), [http://www.rcsb.org/pdb/explore.do?structureId=1R8D 1R8D] (complex of N-terminal domain with DNA)
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P71039 P71039]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU36600]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''mta'' {{PubMed\|9353933}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mta_3764133_3764906_-1 mta] {{PubMed\|22383849}}
−
−	* '''Sigma factor:''' [[SigA]] {{PubMed\|10200972}}
−
−	* '''Regulation:'''
−	** positive autoregulation {{PubMed\|10200972}}
−
−	* '''Regulatory mechanism:'''
−	** Mta: transcription activation {{PubMed\|10200972}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~[[Mohamed Marahiel]], Marburg University, Germany [http://www.uni-marburg.de/fb15/fachgebiete/bio/marahiel?language_sync=1 homepage]~~
−
−	[[Richard Brennan]], Houston, Texas, USA [http://www.mdanderson.org/departments/biochem/display.cfm?id=556ef368-6c81-4043-b74f350d41dd06cb&method=displayfull&pn=a8427ebd-d0ff-11d4-80fd00508b603a14 Homepage]
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−
−	~~<pubmed>18502870,14985361,11581256,11053850,10200972 9353933 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 57: / Line 57: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mta.html]
@@ Line 94: / Line 95: @@
 === Database entries ===
 * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1JBG 1JBG] (N-terminal domain),  [http://www.rcsb.org/pdb/explore.do?structureId=1R8D 1R8D] (complex of N-terminal domain with DNA)

@@ Line 27: / Line 27: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mta_3764133_3764906_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:mta_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mta_3764133_3764906_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:mta_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36600]]
 |-
 |}

@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[clsA]]'', ''[[ywnC]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36600 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36600 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36600 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36600 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36600 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36600 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:mta_context.gif]]

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of multidrug-efflux transporter genes
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU36600 mta]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36600 mta]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.949
@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[clsA]]'', ''[[ywnC]]''
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15677&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36600 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36600 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36600 Advanced_DNA]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:mta_context.gif]]

@@ Line 99: / Line 99: @@
 * '''Operon:''' ''mta'' {{PubMed|9353933}}
-* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|10200972}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mta_3764133_3764906_-1 mta] {{PubMed|22383849}}
 * '''Regulation:'''
@@ Line 107: / Line 109: @@
 ** Mta: transcription activation {{PubMed|10200972}}
 * '''Additional information:'''
 =Biological materials =

@@ Line 79: / Line 79: @@
 * '''Effectors of protein activity:'''
-* '''Interactions:'''
+* '''[[SubtInteract|Interactions]]:'''
-* '''Localization:''' cytoplasm (according to Swiss-Prot)
+* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)
 === Database entries ===

@@ Line 37: / Line 37: @@
 = This gene is a member of the following [[regulons]] =
 {{SubtiWiki regulon|[[Mta regulon]]}}
+=The [[Mta regulon]]=
 =The gene=