MinD - Revision history

Jstuelk: /* Reviews */

2015-08-20T12:50:44Z

‎Reviews

Dtoedter: /* Biological materials */

2015-03-06T10:44:40Z

‎Biological materials

Jstuelk: /* Original Publications */

2014-11-07T10:04:58Z

‎Original Publications

134.76.70.252 at 14:10, 17 April 2014

2014-04-17T14:10:14Z

134.76.70.252 at 09:27, 17 April 2014

2014-04-17T09:27:53Z

134.76.38.147 at 14:24, 2 April 2014

2014-04-02T14:24:06Z

Jstuelk at 14:07, 27 December 2013

2013-12-27T14:07:58Z

Jstuelk at 18:08, 21 December 2013

2013-12-21T18:08:23Z

134.76.70.252 at 09:01, 12 November 2013

2013-11-12T09:01:51Z

134.76.70.252 at 14:09, 16 May 2013

2013-05-16T14:09:47Z

← Older revision		Revision as of 12:50, 20 August 2015
Line 1:		Line 1:
−	* '''Description:''' cell-division inhibitor (septum placement), part of the Min system (with [[DivIVA]], [[MinC]], [[MinJ]]), [[Noc]] and the Min system ensure the efficient utilization of the division site at midcell in by ensuring [[FtsZ\|Z ring]] placement <br/><br/>	+	{{#bank: MinD}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''minD''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''divIVB1 ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| cell-division inhibitor~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| septum placement~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27990 minD]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=MinD MinD]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 29 kDa, 4.984~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 804 bp, 268 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[spoIVFA]]'', ''[[minC]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27990 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27990 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27990 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:minD_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=minD_2857776_2858582_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:minD_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27990]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[cell division]]}},~~
−	~~{{SubtiWiki category\|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[SigH regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[SigM regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU27990
−
−	~~===Phenotypes of a mutant ===~~
−	* a ''[[yvcL]] [[minC]]-[[minD]]'' mutant grows poorly, and the cells are filamentous {{PubMed\|24097947}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27990&redirect=T BSU27990]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mreBCD-minCD.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10330]
−
−	~~=== Additional information===~~
−	* A mutation was found in this gene after evolution under relaxed selection for sporulation {{PubMed\|21821766}}
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:''' The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle {{PubMed\|20352045}}
−
−	* '''Protein family:''' MinD subfamily (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** ([[MinC]]-[[MinD]])-[[MinJ]]-[[DivIVA]] {{PubMed\|20352045}}
−
−	* '''[[Localization]]:'''
−	** polar/ septal at the cell membrane {{PubMed\|20566861}}
−	** membrane binding/ polar localization depends on the proton motive force {{PubMed\|20566861}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27990&redirect=T BSU27990]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/Q01464 Q01464]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27990]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−	* '''Operon:'''
−	** ''[[radC]]-[[mreB]]-[[mreC]]-[[mreD]]-[[minC]]-[[minD]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 PubMed]
−	** ''[[mreB]]-[[mreC]]-[[mreD]]-[[minC]]-[[minD]]'' {{PubMed\|8459776}}
−	** ''[[minC]]-[[minD]]'' {{PubMed\|8459776}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=minD_2857776_2858582_-1 minD] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−	** ''[[radC]]'': [[SigM]] {{PubMed\|18179421}}
−	** ''[[minC]]'': [[SigH]] {{PubMed\|8459776}}
−
−	* '''Regulation:'''
−	** expression is reduced in a [[SigV]] mutant {{PubMed\|21926231}}
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 716 {{PubMed\|24696501}}
−	** number of protein molecules per cell (complex medium with amino acids, without glucose): 813 {{PubMed\|24696501}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 3544 {{PubMed\|21395229}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 1500 {{PubMed\|21395229}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 6195 {{PubMed\|21395229}}
−
−	~~=Biological materials =~~
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:''' ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([[BACTH]]), available in [[Jörg Stülke]]'s lab
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 19884039 24367361</pubmed>~~
−	~~==Original Publications==~~
−	~~<pubmed>8459776,19019154,11886553,9808628,1400224,12368265,10411726,15317782,12492861, 20352045, 11886553 20566861 18179421 21821766 22457634 21926231 24097947 25374563 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 142: / Line 142: @@
 * '''GFP fusion:'''
-* '''two-hybrid system:'''
+* '''two-hybrid system:''' ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([[BACTH]]), available in [[Jörg Stülke]]'s lab
 * '''Antibody:'''

@@ Line 154: / Line 154: @@
 <pubmed> 19884039 24367361</pubmed>
 ==Original Publications==
-<pubmed>8459776,19019154,11886553,9808628,1400224,12368265,10411726,15317782,12492861, 20352045, 11886553 20566861 18179421 21821766 22457634 21926231 24097947 </pubmed>
+<pubmed>8459776,19019154,11886553,9808628,1400224,12368265,10411726,15317782,12492861, 20352045, 11886553 20566861 18179421 21821766 22457634 21926231 24097947 25374563 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 129: / Line 129: @@
 ** number of protein molecules per cell (minimal medium with glucose and ammonium): 716 {{PubMed|24696501}}
 ** number of protein molecules per cell (complex medium with amino acids, without glucose): 813 {{PubMed|24696501}}
 =Biological materials =
 * '''Mutant:'''

← Older revision		Revision as of 09:27, 17 April 2014
Line 127:		Line 127:

	* '''Additional information:'''		* '''Additional information:'''
		+	** number of protein molecules per cell (minimal medium with glucose and ammonium): 716 {{PubMed\|24696501}}
		+	** number of protein molecules per cell (complex medium with amino acids, without glucose): 813 {{PubMed\|24696501}}

	=Biological materials =		=Biological materials =

@@ Line 58: / Line 58: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mreBCD-minCD.html]
@@ Line 96: / Line 97: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 146: / Line 146: @@
 =References=
 ==Reviews==
-<pubmed> 19884039 </pubmed>
+<pubmed> 19884039 24367361</pubmed>
 ==Original Publications==
-<pubmed>8459776,19019154,11886553,9808628,1400224,12368265,10411726,15317782,12492861, 20352045, 11886553 20566861 18179421 21821766 22457634 21926231 24097947</pubmed>
+<pubmed>8459776,19019154,11886553,9808628,1400224,12368265,10411726,15317782,12492861, 20352045, 11886553 20566861 18179421 21821766 22457634 21926231 24097947 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 37: / Line 37: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 59: / Line 55: @@
 ===Phenotypes of a mutant ===
 === Database entries ===
@@ Line 83: / Line 80: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 118: / Line 115: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=minD_2857776_2858582_-1 minD] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 ** ''[[radC]]'': [[SigM]] {{PubMed|18179421}}
 ** ''[[minC]]'': [[SigH]] {{PubMed|8459776}}
@@ Line 151: / Line 148: @@
 <pubmed> 19884039 </pubmed>
 ==Original Publications==
-'''Additional publications:''' {{PubMed|21926231}}
+<pubmed>8459776,19019154,11886553,9808628,1400224,12368265,10411726,15317782,12492861, 20352045, 11886553 20566861 18179421 21821766 22457634 21926231 24097947</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27990 minD]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/MinD MinD]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=MinD MinD]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.984

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=minD_2857776_2858582_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:minD_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=minD_2857776_2858582_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:minD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27990]]
 |-
 |}