Icd - Revision history

Fabian Commichau: /* Biological materials */

2014-12-08T13:38:28Z

‎Biological materials

2014-04-17T14:08:56Z

2014-04-17T09:35:32Z

2014-04-02T14:29:42Z

2014-03-14T08:46:26Z

‎References

2014-03-05T12:53:37Z

2014-02-28T16:37:13Z

2014-01-07T11:26:26Z

2013-12-12T13:46:53Z

‎Extended information on the protein

2013-12-12T13:45:58Z

‎Extended information on the protein

@@ Line 145: / Line 145: @@
 ** number of protein molecules per cell (minimal medium with glucose and ammonium): 37100 {{PubMed|24696501}}
 ** number of protein molecules per cell (complex medium with amino acids, without glucose): 77080 {{PubMed|24696501}}
 =Biological materials =
 * '''Mutant:''' GP666 (spc), GP672 (erm), available in [[Jörg Stülke]]'s lab
 ** 1A1000 ( ''icd''::''spec''), {{PubMed| }}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A1000&Search=1A1000 BGSC]

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 * '''Additional information:'''
 ** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}}
 =Biological materials =

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 ** growth and sporulation defects of the mutant could be partially bypassed by deletion of the major citrate synthase gene (''[[citZ]]'') {{PubMed|10348849}}
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/citZ-icd-mdh.html]
@@ Line 107: / Line 108: @@
 === Database entries ===
 * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HQS 1HQS]

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 =References=
-<pubmed>10656796,12850135 11290745 10348849 11751849 18763711 17726680 16493705 4147570 20389117 9244258 20933603 22517742 24325460 24571712 15378759</pubmed>
+<pubmed>10656796,12850135 11290745 10348849 11751849 18763711 17726680 16493705 4147570 20389117 9244258 20933603 22517742 24325460 24571712 15378759 24616559 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 44: / Line 44: @@
 {{SubtiWiki category|[[carbon core metabolism]]}},
 {{SubtiWiki category|[[membrane proteins]]}},
-{{SubtiWiki category|[[phosphoproteins]]}}
+{{SubtiWiki category|[[phosphoproteins]]}},
 = This gene is a member of the following [[regulons]] =
@@ Line 139: / Line 140: @@
 * '''Additional information:'''
 =Biological materials =
@@ Line 166: / Line 168: @@
 =References=
-<pubmed>10656796,12850135 11290745 10348849 11751849 18763711 17726680 16493705 4147570 20389117 9244258 20933603 22517742 24325460 24571712</pubmed>
+<pubmed>10656796,12850135 11290745 10348849 11751849 18763711 17726680 16493705 4147570 20389117 9244258 20933603 22517742 24325460 24571712 15378759</pubmed>
 [[Category:Protein-coding genes]]

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 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
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 === Additional information===
 =The protein=
@@ Line 86: / Line 79: @@
 === Extended information on the protein ===
-* '''Kinetic information:''' Reversible Michaelis-Menten [http://www.ncbi.nlm.nih.gov/pubmed/4147570 PubMed]
+* '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
@@ Line 95: / Line 90: @@
 ** ''in vitro'' phosphorylated by [[PrkC]] on Thr-138, Thr-147, and Thr-396 {{PubMed|20389117}}
-* '''Cofactor(s):''' Mg<sup>2+</sup>, Mn<sup>2+</sup>, NADP<sup>+</sup>
+* '''[[Cofactors]]:''' Mg<sup>2+</sup>, Mn<sup>2+</sup>, NADP<sup>+</sup>
 * '''Effectors of protein activity:'''
@@ Line 131: / Line 126: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=icd_2979716_2980987_-1 icd] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 ** ''[[citZ]]'': [[SigA]] {{PubMed|8045899}}
 ** ''[[icd]]'': [[SigA]] {{PubMed|8045899}}
@@ Line 171: / Line 166: @@
 =References=
-<pubmed>10656796,12850135 11290745 10348849 11751849 18763711 17726680 16493705 4147570 20389117 9244258 20933603 22517742 24325460 </pubmed>
+<pubmed>10656796,12850135 11290745 10348849 11751849 18763711 17726680 16493705 4147570 20389117 9244258 20933603 22517742 24325460 24571712</pubmed>
 [[Category:Protein-coding genes]]

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 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=Icd Icd]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=icd icd]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 4.833

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 ** homodimer [http://www.ncbi.nlm.nih.gov/pubmed/11290745 PubMed]
 ** [[CitZ]]-[[Mdh]]-[[Icd]] (this is the core of the TCA cycle metabolon)  {{PubMed|20933603}}
-** [[Icd]]-[[Mdh]]  {{PubMed|24325460}}
+** [[Mdh]]-[[Icd]]  {{PubMed|24325460}}
 ** [[GltA]]-[[Icd]]  {{PubMed|20933603}}
 ** [[OdhB]]-[[Icd]]  {{PubMed|20933603}}