HutP - Revision history

134.76.38.147 at 15:11, 2 April 2014

2014-04-02T15:11:55Z

134.76.70.252 at 12:00, 7 January 2014

2014-01-07T12:00:36Z

Jstuelk: /* Reviews */

2013-06-12T08:33:19Z

‎Reviews

Jstuelk at 08:32, 12 June 2013

2013-06-12T08:32:51Z

Jstuelk: /* Original publications */

2013-06-12T08:29:29Z

‎Original publications

134.76.70.252 at 14:57, 16 May 2013

2013-05-16T14:57:59Z

134.76.70.252 at 11:40, 14 May 2013

2013-05-14T11:40:15Z

134.76.70.252 at 14:14, 13 May 2013

2013-05-13T14:14:43Z

Awiechert at 11:56, 5 December 2012

2012-12-05T11:56:19Z

Jstuelk at 13:09, 31 August 2012

2012-08-31T13:09:07Z

← Older revision		Revision as of 15:11, 2 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' transcriptional antiterminator of the ''[[hutH\|hut]]'' operon <br/><br/>~~	+	{{#bank: HutP}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''hutP''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''hutP1 ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| transcriptional antiterminator~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| regulation of histidine utilization~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39340 hutP]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=hutP hutP]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 16 kDa, 6.057~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 453 bp, 151 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yxzL]]'', ''[[hutH]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39340 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:hutP_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hutP_4041483_4041938_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:hutP_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39340]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[utilization of amino acids]]}},~~
−	~~{{SubtiWiki category\|[[transcription factors and their control]]}},~~
−	~~{{SubtiWiki category\|[[RNA binding regulators]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[CcpA regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[CodY regulon]]}}~~
−	~~=The [[HutP regulon]]: ''[[hutH]]-[[hutU]]-[[hutI]]-[[hutG]]-[[hutM]]''=~~
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU39340
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/hut.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10666]
−
−	~~=== Additional information===~~
−
−
−
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' hutP family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−	** HutP binds its RNA target to cause antitermination in the presence of histidine {{PubMed\|23748184}}
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−
−	* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3BOY 3BOY] (complex bound to the hut mRNA), [http://www.rcsb.org/pdb/explore.do?structureId=1WPT 1WPT]
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P10943 P10943]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU39340]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−	* '''Operon:''' ''[[hutP]]-[[hutH]]-[[hutU]]-[[hutI]]-[[hutG]]-[[hutM]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10746760 PubMed]
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hutP_4041483_4041938_1 hutP] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigA]] {{PubMed\|8071225}}
−
−	* '''Regulation:'''
−	** repressed by glucose ([[CcpA]]) {{PubMed\|8071225}}
−	** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8682780 PubMed]
−
−	* '''Regulatory mechanism:'''
−	** [[CcpA]]: transcription repression {{PubMed\|8071225}}
−	** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/8682780 PubMed]
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed>17395359 16427271 22933560</pubmed>~~
−
−	~~==Original publications==~~
−	~~'''Additional publications:''' {{PubMed\|23748184}}~~
−	~~<pubmed>12903241,8682780, 8071225 10217782 18083814 22900538 23748184 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39340 hutP]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/histidine.html His]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=hutP hutP]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 6.057

@@ Line 143: / Line 143: @@
 =References=
 ==Reviews==
-<pubmed>17395359 16427271 22933560 </pubmed>
+<pubmed>17395359 16427271 22933560</pubmed>
 ==Original publications==

@@ Line 36: / Line 36: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/><br/><br/>
+<br/><br/><br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 87: / Line 88: @@
 * '''Effectors of protein activity:'''
 * '''[[SubtInteract|Interactions]]:'''
@@ Line 109: / Line 111: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hutP_4041483_4041938_1 hutP] {{PubMed|22383849}}
-* '''Sigma factor:''' [[SigA]] {{PubMed|8071225}}
+* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8071225}}
 * '''Regulation:'''
@@ Line 144: / Line 146: @@
 ==Original publications==
 <pubmed>12903241,8682780, 8071225 10217782 18083814 22900538 23748184 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 144: / Line 144: @@
 ==Original publications==
-<pubmed>12903241,8682780, 8071225 10217782 18083814 22900538 </pubmed>
+<pubmed>12903241,8682780, 8071225 10217782 18083814 22900538 23748184 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hutP_4041483_4041938_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:hutP_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hutP_4041483_4041938_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:hutP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39340]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yxzL]]'', ''[[hutH]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39340 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39340 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:hutP_context.gif]]

@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 453 bp, 151 aa
 |-
-|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[abn2]]'', ''[[hutH]]''
+|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yxzL]]'', ''[[hutH]]''
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15970&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''