HtrC - Revision history

Jstuelk at 15:39, 14 November 2014

2014-11-14T15:39:51Z

Jstuelk: /* Extended information on the protein */

2014-11-14T15:39:08Z

‎Extended information on the protein

Jstuelk: /* Extended information on the protein */

2014-11-14T15:38:39Z

‎Extended information on the protein

Jstuelk: /* References */

2014-11-14T15:07:35Z

‎References

Jstuelk at 17:16, 15 January 2014

2014-01-15T17:16:48Z

Jstuelk: Jstuelk moved page YyxA to HtrC: 24362423

2014-01-15T17:13:00Z

Jstuelk moved page YyxA to HtrC: 24362423

Jstuelk: /* Expression and regulation */

2014-01-15T17:10:14Z

‎Expression and regulation

Jstuelk at 17:09, 15 January 2014

2014-01-15T17:09:02Z

Jstuelk at 09:35, 3 December 2013

2013-12-03T09:35:01Z

134.76.70.252 at 15:01, 16 May 2013

2013-05-16T15:01:39Z

← Older revision		Revision as of 15:39, 14 November 2014
Line 1:		Line 1:
−	* '''Description:~~''' similar to quality control membrane serine protease [[HtrA]] <br/><br/>~~	+	{{#bank: HtrC}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''htrC''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''yycK, yyxA ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| putative quality control membrane protease~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| unknown~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40360 htrC]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 42 kDa, 5.315~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1200 bp, 400 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yyzO]]'', ''[[walJ]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU40360 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU40360 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU40360 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yyxA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:yyxA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40360]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[proteolysis]]}},~~
−	~~{{SubtiWiki category\|[[sporulation proteins]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[SigG regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU40360
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yycFGHIJ-yyxA.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11054]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' peptidase S1B family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):''' [[HtrA]]
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract\|interactions]] {{PubMed\|21630458}}
−	** [[HtrC]]-[[YpeB]], for [[proteolysis]] of [[YpeB]] during [[germination]] {{PubMed\|25384476}}
−
−	* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
−
−	~~=== Database entries ===~~
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P39668 P39668]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU40360]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:'''
−	** ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[htrC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
−	** ''[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 htrC] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' for ''[[htrC]]'': [[SigG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
−
−	* '''Regulation:'''
−	** expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
−	** ''htrC'' transcript expressed during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
−	** ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[htrC]]'' is induced upon deletion of ''[[htrA]]'' and ''[[htrB]]'' {{PubMed\|24115457}}
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed>21326199 </pubmed>~~
−	~~== Original publications ==~~
−	~~<pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 24115457 25384476 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 85: / Line 85: @@
 * '''[[SubtInteract|Interactions]]:'''
 ** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
-** [[HtrC]]-[[YpeB]], for proteolysis of [[YpeB]] during [[germination]] {{PubMed|25384476}}
+** [[HtrC]]-[[YpeB]], for [[proteolysis]] of [[YpeB]] during [[germination]] {{PubMed|25384476}}
 * '''[[Localization]]:''' cell membrane (according to Swiss-Prot)

@@ Line 85: / Line 85: @@
 * '''[[SubtInteract|Interactions]]:'''
 ** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
 * '''[[Localization]]:''' cell membrane (according to Swiss-Prot)

@@ Line 141: / Line 141: @@
 <pubmed>21326199 </pubmed>
 == Original publications ==
-<pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 24115457 </pubmed>
+<pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 24115457 25384476 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 113: / Line 113: @@
 ** expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
 ** ''htrC'' transcript expressed during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
 * '''Regulatory mechanism:'''
@@ Line 140: / Line 141: @@
 <pubmed>21326199 </pubmed>
 == Original publications ==
-<pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 </pubmed>
+<pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 24115457 </pubmed>
 [[Category:Protein-coding genes]]

← Older revision	Revision as of 17:13, 15 January 2014
(No difference)

@@ Line 102: / Line 102: @@
 =Expression and regulation=
-* '''Operon:''' ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[htrC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
+* '''Operon:'''
+** ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[htrC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
-''[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
+** ''[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 htrC] {{PubMed|22383849}}

@@ Line 1: / Line 1: @@
-* '''Description:''' similar to serine protease HtrA <br/><br/>
+* '''Description:''' similar to quality control membrane serine protease [[HtrA]] <br/><br/>
 {| align="right" border="1" cellpadding="2"
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''yyxA''
+|''htrC''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yycK ''
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yycK, yyxA ''
 |-
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+|style="background:#ABCDEF;" align="center"| '''Product''' || putative quality control membrane protease
 |-
 |style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40360 yyxA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40360 htrC]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.315
@@ Line 75: / Line 75: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
 * '''[[SubtInteract|Interactions]]:'''
-** [[YyxA]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
+** [[HtrC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
 * '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
@@ Line 102: / Line 102: @@
 =Expression and regulation=
-* '''Operon:''' ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
+* '''Operon:''' ''[[walR]]-[[walK]]-[[yycH]]-[[yycI]]-[[walJ]]-[[htrC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
 ''[[yyxA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 yyxA] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 htrC] {{PubMed|22383849}}
-* '''Sigma factor:''' for ''[[yyxA]]'': [[SigG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
+* '''[[Sigma factor]]:''' for ''[[htrC]]'': [[SigG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
-* '''Regulation:''' expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
+* '''Regulation:'''
+** expressed during vegetative growth, repressed during stationary phase [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
-''yyxA'' transcript expressed during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
+** ''htrC'' transcript expressed during sporulation [http://www.ncbi.nlm.nih.gov/sites/entrez/9829949 PubMed]
 * '''Regulatory mechanism:'''
@@ Line 140: / Line 140: @@
 <pubmed>21326199 </pubmed>
 == Original publications ==
-<pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710</pubmed>
+<pubmed>17600057,12270824 ,11555295,18957862, 10692364 21624103 22307758 22092710 24362423 9829949,21630458 </pubmed>
-<pubmed>9829949,21630458, </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 35: / Line 35: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 141: / Line 137: @@
 =References=
 <pubmed>9829949,21630458, </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 27: / Line 27: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yyxA_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrC_4147567_4148769_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yyxA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40360]]
 |-
 |}