HtrB - Revision history

Jstuelk at 10:42, 19 September 2014

2014-09-19T10:42:58Z

134.76.70.252 at 09:37, 17 April 2014

2014-04-17T09:37:28Z

134.76.38.147 at 14:42, 2 April 2014

2014-04-02T14:42:45Z

Jstuelk at 17:01, 20 February 2014

2014-02-20T17:01:56Z

Jstuelk at 16:29, 16 January 2014

2014-01-16T16:29:48Z

134.76.70.252 at 11:38, 7 January 2014

2014-01-07T11:38:12Z

Jstuelk: /* Reviews */

2013-12-03T09:35:40Z

‎Reviews

Jstuelk: /* References */

2013-07-31T13:50:57Z

‎References

134.76.70.252 at 14:31, 16 May 2013

2013-05-16T14:31:41Z

134.76.70.252 at 11:13, 14 May 2013

2013-05-14T11:13:54Z

← Older revision		Revision as of 10:42, 19 September 2014
Line 1:		Line 1:
−	* '''Description:~~''' membrane-anchored protein quality control protease, serine protease, response to secretion and heat stresses <br/><br/>~~	+	{{#bank: HtrB}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''htrB''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''yvtA, yvtB''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| serine protease~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| protein quality control~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33000 htrB]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=htrB htrB]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 48 kDa, 4.632~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1374 bp, 458 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[mrgA]]'', ''[[cssR]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33000 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33000 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33000 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yvtA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrB_3384070_3385446_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:htrB_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33000]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[proteolysis]]}},~~
−	~~{{SubtiWiki category\|[[heat shock proteins]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[CssR regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU33000
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU33000&redirect=T BSU33000]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yvtA.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG14155]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' peptidase S1B family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−	** cell membrane (according to Swiss-Prot)
−	** randomly distributed in foci throughout the cell surface {{PubMed\|22307758}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU33000&redirect=T BSU33000]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/Q9R9I1 Q9R9I1]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU33000]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''htrB'' (according to [http://dbtbs.hgc.jp/COG/prom/yvtA.html DBTBS])
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrB_3384070_3385446_-1 htrB] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−	** expressed under conditions of secretion stress ([[CssR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12270824 PubMed]
−	** induced by rhamnolipids {{PubMed\|22092710}}
−
−	* '''Regulatory mechanism:'''
−	** [[CssR]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/12270824 PubMed]
−
−	* '''Additional information:'''
−	** [[HtrB]] is subject to degradation by [[WprA]] and other extracellular proteases {{PubMed\|24362423}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 153 {{PubMed\|24696501}}
−	** number of protein molecules per cell (complex medium with amino acids, without glucose): 345 {{PubMed\|24696501}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed>22688815 21326199</pubmed>~~
−
−	~~== Original publications ==~~
−	~~<pubmed>17600057,22307758,12270824, 22092710 24362423 24115457 11133960 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 122: / Line 122: @@
 * '''Additional information:'''
 ** [[HtrB]] is subject to degradation by [[WprA]] and other extracellular proteases {{PubMed|24362423}}
 =Biological materials =

@@ Line 56: / Line 56: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yvtA.html]
@@ Line 92: / Line 93: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 144: / Line 144: @@
 == Original publications ==
-<pubmed>17600057,22307758,12270824, 22092710 24362423</pubmed>
+<pubmed>17600057,22307758,12270824, 22092710 24362423 24115457 11133960 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 37: / Line 37: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 62: / Line 62: @@
 === Additional information===
 =The protein=
@@ Line 80: / Line 77: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 112: / Line 109: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrB_3384070_3385446_-1 htrB] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''
@@ Line 122: / Line 119: @@
 * '''Additional information:'''
 =Biological materials =
@@ Line 146: / Line 144: @@
 == Original publications ==
-<pubmed>17600057,22307758,12270824, 22092710</pubmed>
+<pubmed>17600057,22307758,12270824, 22092710 24362423</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33000 htrB]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=htrB htrB]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 48 kDa, 4.632

@@ Line 143: / Line 143: @@
 =References=
 ==Reviews==
-<pubmed>22688815 </pubmed>
+<pubmed>22688815 21326199</pubmed>
 == Original publications ==
 <pubmed>17600057,22307758,12270824, 22092710</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrB_3384070_3385446_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:htrB_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htrB_3384070_3385446_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:htrB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33000]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mrgA]]'', ''[[cssR]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33000 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33000 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33000 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33000 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33000 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33000 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:yvtA_context.gif]]