HtpX - Revision history

134.76.70.252 at 11:25, 17 April 2014

2014-04-17T11:25:24Z

134.76.38.147 at 13:32, 2 April 2014

2014-04-02T13:32:19Z

134.76.70.252 at 13:06, 16 May 2013

2013-05-16T13:06:17Z

134.76.70.252 at 10:02, 14 May 2013

2013-05-14T10:02:12Z

134.76.70.252 at 12:39, 13 May 2013

2013-05-13T12:39:35Z

Jstuelk at 17:58, 14 October 2012

2012-10-14T17:58:56Z

Jstuelk at 08:08, 9 October 2012

2012-10-09T08:08:36Z

Jstuelk: moved YkrL to HtpX: 23042994

2012-10-09T08:05:19Z

moved YkrL to HtpX: 23042994

134.76.70.252 at 08:52, 7 August 2012

2012-08-07T08:52:40Z

Jstuelk at 14:56, 4 June 2012

2012-06-04T14:56:26Z

← Older revision		Revision as of 11:25, 17 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' stress-responsive membrane protease<br/><br/>~~	+	{{#bank: HtpX}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''htpX''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''ykrL ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| membrane protease~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| quality control of membrane proteins~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13490 htpX]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 32 kDa, 10.157~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 894 bp, 298 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[ykrK]]'', ''[[ktrD]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13490 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:ykrL_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htpX_1414997_1415893_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:ykrL_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13490]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}},~~
−	~~{{SubtiWiki category\|[[proteolysis]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[Rok regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[YkrK regulon]]}},~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU13490
−
−	~~===Phenotypes of a mutant ===~~
−	* increased sensitivity to membrane protein overproduction {{PubMed\|22447908}}
−	* increased sensitivity to dissipation of the membrane potential by the addition of valinomycin {{PubMed\|22447908}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13490&redirect=T BSU13490]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13274]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' peptidase M48B family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−	** cell membrane (according to Swiss-Prot)
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13490&redirect=T BSU13490]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/O31657 O31657]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU13490]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[htpX]]'' {{PubMed\|22383849}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htpX_1414997_1415893_1 htpX] {{PubMed\|22383849}}
−
−	* '''Sigma factor:'''
−
−	* '''Regulation:'''
−	** induced by membrane protein overproduction ([[YkrK]]) {{PubMed\|22624725,22447908}}
−	** induced by dissipation of membrane potential (ΔΨ) by addition of a sublethal concentration of valinomycin {{PubMed\|22447908}}
−	** expression is increased due to mutations in ''[[resE]]'', ''[[resB]]'', ''[[sdhC]]'', and'' [[sdhA]]'' {{PubMed\|22447908}}
−	** induced by salt stress {{PubMed\|22447908}}
−
−	* '''Regulatory mechanism:'''
−	** [[YkrK]]: transcription repression {{PubMed\|22447908}}
−	** [[Rok]]: transcription repression {{PubMed\|22447908}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~<pubmed> 22447908 22624725 22383849 23042994 </pubmed>~~
−	~~[[Category:Protein-coding genes]]~~

@@ Line 56: / Line 56: @@
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 91: / Line 92: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 27: / Line 27: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htpX_1414997_1415893_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ykrL_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htpX_1414997_1415893_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ykrL_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13490]]
 |-
 |}

@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykrK]]'', ''[[ktrD]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13490 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13490 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:ykrL_context.gif]]

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || quality control of membrane proteins
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13490 htpX]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13490 htpX]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 10.157
@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykrK]]'', ''[[ktrD]]''
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13222&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13490 Advanced_DNA]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:ykrL_context.gif]]

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || quality control of membrane proteins
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13490 ykrL]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13490 htpX]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 10.157
@@ Line 104: / Line 104: @@
 =Expression and regulation=
-* '''Operon:''' ''[[ykrL]]'' {{PubMed|22383849}}
+* '''Operon:''' ''[[htpX]]'' {{PubMed|22383849}}
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htpX_1414997_1415893_1 ykrL] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htpX_1414997_1415893_1 htpX] {{PubMed|22383849}}
 * '''Sigma factor:'''

@@ Line 1: / Line 1: @@
-* '''Description:''' similar to ''E.coli'' HtpX heat shock protease, stress-responsive membrane protease<br/><br/>
+* '''Description:''' stress-responsive membrane protease<br/><br/>
 {| align="right" border="1" cellpadding="2"
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''ykrL''
+|''htpX''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''htpX ''
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ykrL ''
 |-
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
@@ Line 35: / Line 35: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 91: / Line 87: @@
 * '''[[SubtInteract|Interactions]]:'''
-* '''Localization:''' cell membrane (according to Swiss-Prot)
+* '''[[Localization]]:'''
 === Database entries ===
@@ Line 144: / Line 141: @@
 =References=
-<pubmed> 22447908 22624725 22383849</pubmed>
+<pubmed> 22447908 22624725 22383849 23042994 </pubmed>
 [[Category:Protein-coding genes]]

← Older revision	Revision as of 08:05, 9 October 2012
(No difference)

@@ Line 105: / Line 105: @@
 =Expression and regulation=
-* '''Operon:'''
+* '''Operon:''' ''[[ykrL]]'' {{PubMed|22383849}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=htpX_1414997_1415893_1 ykrL] {{PubMed|22383849}}
@@ Line 112: / Line 112: @@
 * '''Regulation:'''
-** induced by membrane protein overproduction ([[YkrK]]) {{PubMed|22447908}}
+** induced by membrane protein overproduction ([[YkrK]]) {{PubMed|22624725,22447908}}
 ** induced by dissipation of membrane potential (ΔΨ) by addition of a sublethal concentration of valinomycin {{PubMed|22447908}}
 ** expression is increased due to mutations in ''[[resE]]'', ''[[resB]]'', ''[[sdhC]]'', and'' [[sdhA]]'' {{PubMed|22447908}}
@@ Line 142: / Line 142: @@
 =References=
-<pubmed> 22447908 </pubmed>
+<pubmed> 22447908 22624725 22383849</pubmed>
 [[Category:Protein-coding genes]]