GlxA - Revision history

Fabian Commichau: /* Biological materials */

2014-12-08T13:27:16Z

‎Biological materials

134.76.70.252 at 14:22, 17 April 2014

2014-04-17T14:22:33Z

134.76.70.252 at 11:26, 17 April 2014

2014-04-17T11:26:04Z

Jstuelk: /* Categories containing this gene/protein */

2014-02-19T09:32:55Z

‎Categories containing this gene/protein

Jstuelk at 17:37, 14 February 2014

2014-02-14T17:37:44Z

Jstuelk: /* Basic information/ Evolution */

2014-02-14T17:32:08Z

‎Basic information/ Evolution

Jstuelk at 17:21, 14 February 2014

2014-02-14T17:21:06Z

Jstuelk at 16:44, 14 February 2014

2014-02-14T16:44:26Z

Jstuelk: Jstuelk moved page YwbC to GlxA: 24330391

2014-02-14T16:42:46Z

Jstuelk moved page YwbC to GlxA: 24330391

Jstuelk at 18:04, 7 January 2014

2014-01-07T18:04:42Z

← Older revision		Revision as of 13:27, 8 December 2014
Line 1:		Line 1:
−	* '''Description:~~''' glyoxalase I <br/><br/>~~	+	{{#bank: GlxA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''glxA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''ipa-18r, ywbC ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| glyoxalase I~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| detoxification of methylglyoxal~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38370 glxA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=ywbC glxA]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 14 kDa, 4.429~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 378 bp, 126 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[ywbD]]'', ''[[ywbB]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38370 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38370 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38370 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:ywbC_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywbC_3937135_3937515_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:ywbC_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38370]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[resistance against oxidative and electrophile stress]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU38370
−
−	~~===Phenotypes of a mutant ===~~
−	* increased sensitivity to methylglyoxal {{PubMed\|24330391}}
−
−	~~=== Database entries ===~~
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ywbC.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10564]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−	** methylglyoxal + BSH --> S-lactoyl-bacillithiol (BSH) {{PubMed\|24330391}}
−
−	* '''Protein family:''' glyoxalase I family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P39586 P39586]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU38370]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''glxA'' {{PubMed\|9353933}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywbC_3937135_3937515_1 glxA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 229 {{PubMed\|24696501}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 3299 {{PubMed\|21395229}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 1387 {{PubMed\|21395229}}
−	** number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 2906 {{PubMed\|21395229}}
−
−	~~=Biological materials =~~
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~<pubmed>9353933 24330391 </pubmed>~~
−	~~[[Category:Protein-coding genes]]~~

@@ Line 115: / Line 115: @@
 * '''Additional information:'''
 ** number of protein molecules per cell (minimal medium with glucose and ammonium): 229 {{PubMed|24696501}}
 =Biological materials =
 * '''Mutant:'''

← Older revision		Revision as of 11:26, 17 April 2014
Line 114:		Line 114:

	* '''Additional information:'''		* '''Additional information:'''
		+	** number of protein molecules per cell (minimal medium with glucose and ammonium): 229 {{PubMed\|24696501}}

	=Biological materials =		=Biological materials =

@@ Line 40: / Line 40: @@
 = [[Categories]] containing this gene/protein =
-{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}},
+{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}
 = This gene is a member of the following [[regulons]] =

← Older revision		Revision as of 17:37, 14 February 2014
Line 53:		Line 53:

	===Phenotypes of a mutant ===		===Phenotypes of a mutant ===
		+	* increased sensitivity to methylglyoxal {{PubMed\|24330391}}

	=== Database entries ===		=== Database entries ===

@@ Line 67: / Line 67: @@
 * '''Catalyzed reaction/ biological activity:'''
-** methylglyoxal --> D-lactate {{PubMed|24330391}}
+** methylglyoxal + BSH --> S-lactoyl-bacillithiol (BSH) {{PubMed|24330391}}
 * '''Protein family:''' glyoxalase I family (according to Swiss-Prot)

← Older revision		Revision as of 17:21, 14 February 2014
Line 67:		Line 67:

	* '''Catalyzed reaction/ biological activity:'''		* '''Catalyzed reaction/ biological activity:'''
		+	** methylglyoxal --> D-lactate {{PubMed\|24330391}}

	* '''Protein family:''' glyoxalase I family (according to Swiss-Prot)		* '''Protein family:''' glyoxalase I family (according to Swiss-Prot)

@@ Line 4: / Line 4: @@
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''ywbC''
+|''glxA''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ipa-18r ''
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ipa-18r, ywbC ''
 |-
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of methylglyoxal
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38370 ywbC]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38370 glxA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=ywbC ywbC]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=ywbC glxA]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 4.429
@@ Line 61: / Line 61: @@
 === Additional information===
 =The protein=
@@ Line 103: / Line 102: @@
 =Expression and regulation=
-* '''Operon:''' ''ywbC'' {{PubMed|9353933}}
+* '''Operon:''' ''glxA'' {{PubMed|9353933}}
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywbC_3937135_3937515_1 ywbC] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywbC_3937135_3937515_1 glxA] {{PubMed|22383849}}
 * '''[[Sigma factor]]:'''

← Older revision	Revision as of 16:42, 14 February 2014
(No difference)

@@ Line 1: / Line 1: @@
-* '''Description:''' putative methylglyoxalase <br/><br/>
+* '''Description:''' glyoxalase I  <br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 10: / Line 10: @@
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || putative methylglyoxalase
+|style="background:#ABCDEF;" align="center"| '''Product''' || glyoxalase I
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+|style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of methylglyoxal
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38370 ywbC]
@@ Line 37: / Line 37: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 65: / Line 61: @@
 === Additional information===
@@ Line 83: / Line 77: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
-* '''Interactions:'''
+* '''[[SubtInteract|Interactions]]:'''
-* '''Localization:'''
+* '''[[Localization]]:'''
 === Database entries ===
@@ Line 113: / Line 107: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywbC_3937135_3937515_1 ywbC] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''
@@ Line 140: / Line 134: @@
 =References=
-<pubmed>9353933  </pubmed>
+<pubmed>9353933  24330391 </pubmed>
 [[Category:Protein-coding genes]]