GamP - Revision history

134.76.70.252 at 09:56, 17 April 2014

2014-04-17T09:56:36Z

134.76.38.147 at 12:53, 2 April 2014

2014-04-02T12:53:59Z

Jstuelk at 10:53, 31 March 2014

2014-03-31T10:53:54Z

Jstuelk at 07:44, 31 March 2014

2014-03-31T07:44:08Z

134.76.70.252 at 10:04, 7 January 2014

2014-01-07T10:04:43Z

Jstuelk: /* References */

2013-12-18T11:33:17Z

‎References

134.76.70.252 at 15:06, 11 November 2013

2013-11-11T15:06:42Z

Jstuelk: /* Basic information/ Evolution */

2013-08-30T08:02:06Z

‎Basic information/ Evolution

Jstuelk at 16:55, 24 May 2013

2013-05-24T16:55:20Z

134.76.70.252 at 12:27, 16 May 2013

2013-05-16T12:27:24Z

← Older revision		Revision as of 09:56, 17 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' glucosamine-specific [[PTS\|phosphotransferase system]], EIICBA of the [[PTS]] <br/><br/>~~	+	{{#bank: GamP}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''gamP''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''ybfS, yzfA ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| glucosamine-specific [[PTS\|phosphotransferase system]], EIICBA~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| glucosamine uptake and phosphorylation~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02350 gamP]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=GamP GamP]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=gamP gamP]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 67 kDa, 5.472~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1893 bp, 631 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[gltP]]'', ''[[gamA]]''~~
−	\|-
−	~~\|style="background:#FAF8CC;" align="center"\|'''[http://subtiwiki.uni-goettingen.de/gamP_nucleotide.txt Gene sequence (+200bp) ]'''~~
−	~~\|style="background:#FAF8CC;" align="center"\|'''[http://subtiwiki.uni-goettingen.de/gamP_protein.txt Protein sequence]'''~~
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:gamP_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nagP_254907_256802_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:gamP_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02350]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[cell wall degradation/ turnover]]}},~~
−	~~{{SubtiWiki category\|[[phosphotransferase systems]]}},~~
−	~~{{SubtiWiki category\|[[utilization of specific carbon sources]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}},~~
−	~~{{SubtiWiki category\|[[phosphoproteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[GamR regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU02350
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~delayed growth with glucosamine as the single carbon source [http://www.ncbi.nlm.nih.gov/sites/entrez/10627040 PubMed]~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02350&redirect=T BSU02350]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11014]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:''' protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
−
−	* '''Protein family:''' [[PTS]] permease, glucose permease (Glc) family [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed]
−
−	* '''Paralogous protein(s):''' [[NagP]]
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:''' [[GamP]]-[[PtsH\|HPr]]
−
−	* '''[[Localization]]:''' membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02350&redirect=T BSU02350]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P39816 P39816]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU02350]
−
−	* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.1.69 2.7.1.69]
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[gamA]]-[[gamP]]'' {{PubMed\|23667565}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nagP_254907_256802_-1 gamP] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigA]] {{PubMed\|23667565}}
−
−	* '''Regulation:'''
−	** induced by glucosamine ([[GamR]]) {{PubMed\|24673833,23667565}}
−
−	* '''Regulatory mechanism:'''
−	** [[GamR]]: transcription repression {{PubMed\|24673833,23667565}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:''' QB6098 (aphA3), available in [[Stülke]] lab
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−
−	~~<pubmed>10627040 18763711 24673833,23667565, </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 63: / Line 63: @@
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 97: / Line 98: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 117: / Line 117: @@
 * '''Regulation:'''
-** induced by glucosamine ([[GamR]]) {{PubMed|23667565}}
+** induced by glucosamine ([[GamR]]) {{PubMed|24673833,23667565}}
 * '''Regulatory mechanism:'''
-** [[GamR]]: transcription repression {{PubMed|23667565}}
+** [[GamR]]: transcription repression {{PubMed|24673833,23667565}}
 * '''Additional information:'''
@@ Line 144: / Line 144: @@
 =References=
-<pubmed>10627040 18763711 23667565, </pubmed>
+<pubmed>10627040 18763711 24673833,23667565, </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 50: / Line 50: @@
 = This gene is a member of the following [[regulons]] =
-{{SubtiWiki regulon|[[YbgA regulon]]}}
+{{SubtiWiki regulon|[[GamR regulon]]}}
 =The gene=
@@ Line 69: / Line 69: @@
 === Additional information===
 =The protein=
@@ Line 87: / Line 84: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 120: / Line 117: @@
 * '''Regulation:'''
-** induced by glucosamine ([[YbgA]]) {{PubMed|23667565}}
+** induced by glucosamine ([[GamR]]) {{PubMed|23667565}}
 * '''Regulatory mechanism:'''
-** [[YbgA]]: transcription repression {{PubMed|23667565}}
+** [[GamR]]: transcription repression {{PubMed|23667565}}
 * '''Additional information:'''

@@ Line 18: / Line 18: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=GamP GamP]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=gamP gamP]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 67 kDa, 5.472

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02350 gamP]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/GamP GamP]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=GamP GamP]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''

@@ Line 81: / Line 81: @@
 * '''Protein family:''' [[PTS]] permease, glucose permease (Glc) family [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed]
-* '''Paralogous protein(s):'''
+* '''Paralogous protein(s):''' [[NagP]]
 === Extended information on the protein ===

@@ Line 40: / Line 40: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 54: / Line 50: @@
 = This gene is a member of the following [[regulons]] =
+{{SubtiWiki regulon|[[YbgA regulon]]}}
 =The gene=
@@ Line 117: / Line 113: @@
 =Expression and regulation=
-* '''Operon:''' ''[[gamA]]-[[gamP]]''
+* '''Operon:''' ''[[gamA]]-[[gamP]]'' {{PubMed|23667565}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nagP_254907_256802_-1 gamP] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|23667565}}
 * '''Regulation:'''
 * '''Regulatory mechanism:'''
 * '''Additional information:'''

@@ Line 32: / Line 32: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nagP_254907_256802_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:gamP_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nagP_254907_256802_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:gamP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02350]]
 |-
 |}