DapI - Revision history

134.76.70.252 at 11:25, 17 April 2014

2014-04-17T11:25:05Z

134.76.70.252 at 11:42, 8 April 2014

2014-04-08T11:42:49Z

Jstuelk at 13:43, 5 January 2014

2014-01-05T13:43:25Z

Jstuelk at 12:14, 5 January 2014

2014-01-05T12:14:32Z

Jstuelk: /* Expression and regulation */

2014-01-05T12:12:48Z

‎Expression and regulation

Jstuelk at 12:01, 5 January 2014

2014-01-05T12:01:09Z

Jstuelk: Jstuelk moved page YkuR to DapI: 24261876

2014-01-05T11:53:31Z

Jstuelk moved page YkuR to DapI: 24261876

Jstuelk: /* Basic information/ Evolution */

2013-08-18T11:36:21Z

‎Basic information/ Evolution

134.76.70.252 at 13:09, 16 May 2013

2013-05-16T13:09:22Z

134.76.70.252 at 10:05, 14 May 2013

2013-05-14T10:05:03Z

← Older revision		Revision as of 11:25, 17 April 2014
Line 123:		Line 123:

	* '''Additional information:'''		* '''Additional information:'''
		+	** number of protein molecules per cell (minimal medium with glucose and ammonium): 274 {{PubMed\|24696501}}
		+	** number of protein molecules per cell (complex medium with amino acids, without glucose): 637 {{PubMed\|24696501}}

	=Biological materials =		=Biological materials =

@@ Line 18: / Line 18: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=DapI DapI]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in  [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=DapI DapI]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 5.102

@@ Line 57: / Line 57: @@
 ===Phenotypes of a mutant ===
+* essential {{PubMed|24261876,12682299}}
-essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
+* depletion of DapI results in swelling and rounding up of cells prior to lysis {{PubMed|24261876}}
 === Database entries ===
@@ Line 92: / Line 92: @@
 * '''[[SubtInteract|Interactions]]:'''
 ** [[DapI]]-[[MreB]] {{PubMed|24261876}}

@@ Line 15: / Line 15: @@
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14190 dapI]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''

@@ Line 111: / Line 111: @@
 * '''Operon:'''
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapL_1489753_1490877_1 ykuR] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapL_1489753_1490877_1 dapI] {{PubMed|22383849}}
 * '''[[Sigma factor]]:'''
@@ Line 119: / Line 119: @@
 * '''Regulatory mechanism:'''
 * '''Additional information:'''
 =Biological materials =

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of lysine and peptidoglycan
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14190 ykuR]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14190 dapI]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
@@ Line 71: / Line 71: @@
 === Basic information/ Evolution ===
-* '''Catalyzed reaction/ biological activity:''' N-acetyl-LL-2,6-diaminoheptanedioate + H<sub>2</sub>O = acetate + LL-2,6-diaminoheptanedioate (according to Swiss-Prot)
+* '''Catalyzed reaction/ biological activity:''' N-acetyl-LL-2,6-diaminopimelate + H<sub>2</sub>O --> acetate + LL-2,6-diaminopimelate {{PubMed|24261876}}
 * '''Protein family:''' peptidase M20A family (according to Swiss-Prot)
@@ Line 81: / Line 81: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
 * '''[[SubtInteract|Interactions]]:'''
 * '''[[Localization]]:'''
 === Database entries ===
@@ Line 118: / Line 120: @@
 * '''Additional information:'''
 =Biological materials =
@@ Line 139: / Line 140: @@
 =References=
+<pubmed>24261876 </pubmed>
 [[Category:Protein-coding genes]]

← Older revision	Revision as of 11:53, 5 January 2014
(No difference)

@@ Line 75: / Line 75: @@
 * '''Protein family:''' peptidase M20A family (according to Swiss-Prot)
-* '''Paralogous protein(s):'''
+* '''Paralogous protein(s):''' [[SndA]], [[SndB]], [[SndC]]
 === Extended information on the protein ===

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapL_1489753_1490877_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ykuR_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapL_1489753_1490877_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ykuR_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14190]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykuQ]]'', ''[[ykuS]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14190 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14190 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14190 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14190 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14190 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14190 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:ykuR_context.gif]]