CotA - Revision history

Jstuelk: /* Original publications */

2015-07-02T09:10:07Z

‎Original publications

Jstuelk: /* Original publications */

2015-04-09T06:48:34Z

‎Original publications

Jstuelk: /* Expression and regulation */

2015-04-06T13:34:28Z

‎Expression and regulation

Jstuelk: /* Original publications */

2014-09-29T09:31:10Z

‎Original publications

Jstuelk: /* References */

2014-04-16T09:30:27Z

‎References

134.76.38.147 at 13:07, 2 April 2014

2014-04-02T13:07:36Z

Jstuelk at 19:00, 4 January 2014

2014-01-04T19:00:30Z

Jstuelk at 08:41, 3 December 2013

2013-12-03T08:41:20Z

Jstuelk at 16:23, 13 August 2013

2013-08-13T16:23:17Z

Jstuelk: /* References */

2013-07-25T16:35:35Z

‎References

← Older revision		Revision as of 09:10, 2 July 2015
Line 1:		Line 1:
−	* '''Description:''' laccase, bilirubin oxidase, spore coat protein (outer) <br/><br/>	+	{{#bank: CotA}}
−	{~~\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''cotA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''pig ''~~
−	\|-
−	~~\|style="background:~~#~~ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background~~:~~#ABCDEF;" align="center"\| '''Product''' \|\| laccase, bilirubin oxidase~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| resistance of the spore~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU06300 cotA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 58 kDa, 5.89~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1539 bp, 513 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yeaA]]'', ''[[gabP]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU06300 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU06300 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU06300 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:cotA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	~~\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotA_683462_685003_-1 Expression at a glance]'''   {{PubMed\|22383849}~~}~~<br/>[[Image:cotA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU06300]]~~
−	\|-
−	\|}

−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[sporulation proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[GerE regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[SigK regulon]]}},~~
−	~~[[Efp-dependent proteins]]~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU06300
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU06300&redirect=T BSU06300]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/cotA.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10490]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:'''
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−
−	* '''[[Localization]]:'''
−	** outer spore coat, more abundant at the mother cell-distal pole of the forespore, localization depends on [[CotE]] {{PubMed\|22171814,19933362}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU06300&redirect=T BSU06300]
−
−	* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BHF 2BHF] (reduced form)
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P07788 P07788]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU06300]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''cotA'' {{PubMed\|22383849}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotA_683462_685003_-1 cotA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigK]] {{PubMed\|15699190,3135411}}
−
−	* '''Regulation:'''
−	** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed\|15383836}}
−
−	* '''Regulatory mechanism:'''
−	** [[GerE]]: transcription repression {{PubMed\|15383836}}
−
−	* '''Additional information:'''
−	** [[translation]] is likely to require [[Efp]] due to the presence of several consecutive proline residues {{PubMed\|23239624,23239623}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−	** 1S101 ( ''cotA''::''cat''), {{PubMed\|2821284}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S101&Search=1S101 BGSC]
−	** 1S134 ( ''cotA''::''kan''), {{PubMed\|11514528}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S134&Search=1S134 BGSC]
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~== Reviews ==~~
−	~~<pubmed>23202530</pubmed>~~
−	~~== Original publications ==~~
−	~~<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 24733162 25259857 25847445</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 142: / Line 142: @@
 <pubmed>23202530</pubmed>
 == Original publications ==
-<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 24733162 25259857 </pubmed>
+<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 24733162 25259857 25847445</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 103: / Line 103: @@
 =Expression and regulation=
-* '''Operon:''' ''cotA'' (according to [http://dbtbs.hgc.jp/COG/prom/cotA.html DBTBS])
+* '''Operon:''' ''cotA'' {{PubMed|22383849}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotA_683462_685003_-1 cotA] {{PubMed|22383849}}

@@ Line 142: / Line 142: @@
 <pubmed>23202530</pubmed>
 == Original publications ==
-<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 24733162 </pubmed>
+<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 24733162 25259857 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 142: / Line 142: @@
 <pubmed>23202530</pubmed>
 == Original publications ==
-<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 </pubmed>
+<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 24733162 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 53: / Line 53: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/cotA.html]
@@ Line 88: / Line 89: @@
 === Database entries ===
 * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BHF 2BHF] (reduced form)

@@ Line 59: / Line 59: @@
 === Additional information===
 =The protein=
@@ Line 77: / Line 74: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
@@ Line 140: / Line 137: @@
 =References=
 <pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 81: / Line 81: @@
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 140: / Line 140: @@
 =References=
-<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836</pubmed>
+<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836 24293734 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 40: / Line 40: @@
 = This gene is a member of the following [[regulons]] =
 {{SubtiWiki regulon|[[SigK regulon]]}},
 [[Efp-dependent proteins]]
@@ Line 87: / Line 88: @@
 * '''[[Localization]]:'''
-** outer spore coat, more abundant at the mother cell-distal pole of the forespore  {{PubMed|19933362}}
+** outer spore coat, more abundant at the mother cell-distal pole of the forespore, localization depends on [[CotE]]  {{PubMed|22171814,19933362}}
 === Database entries ===
@@ Line 110: / Line 111: @@
 * '''Regulation:'''
 * '''Regulatory mechanism:'''
 * '''Additional information:'''
@@ Line 137: / Line 140: @@
 =References=
-<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22410485</pubmed>
+<pubmed>15699190,3135411,11514528,1518043,2821284, 19933362, 20200715 20551082 20822511 21369750 22281748 23859715 22171814 22410485 15383836</pubmed>
 [[Category:Protein-coding genes]]