ComX - Revision history

Jstuelk: /* Original publications */

2015-08-17T08:46:59Z

‎Original publications

Jstuelk: /* Original publications */

2015-03-13T15:41:04Z

‎Original publications

Jstuelk at 08:08, 5 May 2014

2014-05-05T08:08:21Z

134.76.38.147 at 14:38, 2 April 2014

2014-04-02T14:38:48Z

Jstuelk at 12:18, 17 January 2014

2014-01-17T12:18:07Z

Jstuelk: /* Phenotypes of a mutant */

2013-12-04T20:18:34Z

‎Phenotypes of a mutant

Jstuelk at 20:06, 4 December 2013

2013-12-04T20:06:14Z

134.76.70.252 at 09:16, 12 November 2013

2013-11-12T09:16:31Z

134.76.70.252 at 14:27, 16 May 2013

2013-05-16T14:27:37Z

134.76.70.252 at 11:09, 14 May 2013

2013-05-14T11:09:30Z

← Older revision		Revision as of 08:46, 17 August 2015
Line 1:		Line 1:
−	* '''Description:~~''' competence pheromone precursor, transfers cell density signal to [[ComP]]; triggers the production of surfactin <br/><br/>~~	+	{{#bank: ComX}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''comX''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| competence pheromone precursor~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| [[quorum sensing]]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31700 comX]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ComX ComX]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 6 kDa, 4.358~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 165 bp, 55 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[comP]]'', ''[[comQ]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31700 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31700 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31700 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:comX_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comX_3255853_3256020_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:comX_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31700]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[genetic competence]]}},~~
−	~~{{SubtiWiki category\|[[quorum sensing]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU31700
−
−	~~===Phenotypes of a mutant ===~~
−	* the mutation suppresses the mucoid phenotype of ''[[motA]]'' or ''[[motB]]'' mutants due to loss of [[DegU]] phosphorylation and concomitant reduced expression of the ''[[capB]]-[[capC]]-[[capA]]-[[capE]]'' operon {{PubMed\|24296669}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31700&redirect=T BSU31700]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comQX.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11324]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:'''
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−	** is synthesized as an inactive precursor, cleaved, and modified (prenylated) by [[ComQ]] prior to excretion {{PubMed\|22878193}}
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[ComQ]]-[[ComX]] {{PubMed\|22878193}}
−
−	* '''[[Localization]]:'''
−	** secreted (according to Swiss-Prot)
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31700&redirect=T BSU31700]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P45453 P45453]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU31700]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[comQ]]-[[comX]]'' {{PubMed\|1715859}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comX_3255853_3256020_-1 comX] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigA]] {{PubMed\|1715859}}
−
−	* '''Regulation:'''
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~The ComX --> surfactin signaling pathway is an example for paracrine signaling in bacteria~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 22024380 </pubmed>~~
−	~~==Original publications==~~
−	~~<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 24425772 24788106 25757097</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 144: / Line 144: @@
 <pubmed> 22024380 </pubmed>
 ==Original publications==
-<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 24425772 24788106 </pubmed>
+<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 24425772 24788106 25757097</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 144: / Line 144: @@
 <pubmed> 22024380 </pubmed>
 ==Original publications==
-<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 24425772 </pubmed>
+<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 24425772 24788106 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 56: / Line 56: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comQX.html]
@@ Line 93: / Line 94: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 62: / Line 62: @@
 === Additional information===
 =The protein=
@@ Line 143: / Line 142: @@
 <pubmed> 22024380 </pubmed>
 ==Original publications==
-<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 </pubmed>
+<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 24425772 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 53: / Line 53: @@
 ===Phenotypes of a mutant ===
-* the mutation suppresses the mucoid phenotype of ''[[motA]]'' or ''[[motB]]'' mutants due to loss of [[DegU]] phosphorylation and concomitant reduced expression of the ''[[pgsB]]-[[pgsC]]-[[pgsA]]'' operon {{PubMed|24296669}}
+* the mutation suppresses the mucoid phenotype of ''[[motA]]'' or ''[[motB]]'' mutants due to loss of [[DegU]] phosphorylation and concomitant reduced expression of the ''[[capB]]-[[capC]]-[[capA]]-[[capE]]'' operon {{PubMed|24296669}}
 === Database entries ===

@@ Line 37: / Line 37: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 54: / Line 53: @@
 ===Phenotypes of a mutant ===
 === Database entries ===
@@ Line 78: / Line 78: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
-* '''Modification:''' is synthesized as an inactive precursor, cleaved, and modified (prenylated) by [[ComQ]] prior to excretion {{PubMed|22878193}}
+* '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 110: / Line 111: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comX_3255853_3256020_-1 comX] {{PubMed|22383849}}
-* '''Sigma factor:''' [[SigA]] {{PubMed|1715859}}
+* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1715859}}
 * '''Regulation:'''
@@ Line 142: / Line 143: @@
 <pubmed> 22024380 </pubmed>
 ==Original publications==
-'''Additional publications:''' {{PubMed|22511326,21636272}}
+<pubmed>16407988,11133937,12067344,19202088,14679219,15564679,17240141,19605685, 1715859 22878193 24296669 22511326,21636272 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31700 comX]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComX ComX]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ComX ComX]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6 kDa, 4.358

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comX_3255853_3256020_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:comX_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comX_3255853_3256020_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:comX_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31700]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comP]]'', ''[[comQ]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31700 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31700 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31700 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31700 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31700 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31700 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:comX_context.gif]]