BmrC - Revision history

Jstuelk: /* This gene is a member of the following regulons */

2014-09-19T08:46:05Z

‎This gene is a member of the following regulons

Jstuelk: /* Expression and regulation */

2014-09-19T08:42:41Z

‎Expression and regulation

Jstuelk at 08:38, 19 September 2014

2014-09-19T08:38:48Z

Julian at 12:49, 24 April 2014

2014-04-24T12:49:49Z

Julian at 10:58, 24 April 2014

2014-04-24T10:58:23Z

Julian at 08:49, 23 April 2014

2014-04-23T08:49:42Z

134.76.38.147 at 13:18, 2 April 2014

2014-04-02T13:18:49Z

134.76.70.252 at 14:14, 18 November 2013

2013-11-18T14:14:55Z

134.76.70.252 at 12:52, 16 May 2013

2013-05-16T12:52:56Z

134.76.70.252 at 09:48, 14 May 2013

2013-05-14T09:48:54Z

← Older revision		Revision as of 08:46, 19 September 2014
Line 1:		Line 1:
−	* '''Description:''' multidrug [[ABC transporter]] (ATP-binding protein), also involved in the signalling pathway to activate [[KinA]] at the onset of sporulation <br/><br/>	+	{{#bank: BmrC}}
−	{~~\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''bmrC''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''yheI ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| multidrug [[ABC transporter]] (ATP-binding protein)~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| multiple antibiotic resistance~~
−	\|-
−	~~\|colspan="2" style="background:~~#~~FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http~~:~~//subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU09710 bmrC]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=BmrC ~~BmrC]~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 64 kDa, 6.252~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1755 bp, 585 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[yheJ]]'', ''[[bmrD]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU09710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU09710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU09710 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yheI_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	~~\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yheI_1045318_1047075_1 Expression at a glance]'''   {{PubMed\|22383849~~}~~}<br/>[[Image:bmrC_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU09710]]~~
−	\|-
−	\|}

−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[ABC transporters]]}},~~
−	~~{{SubtiWiki category\|[[resistance against toxins/ antibiotics]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}},~~
−	~~{{SubtiWiki category\|[[sporulation proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU09710
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU09710&redirect=T BSU09710]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13041]
−
−	~~=== Additional information===~~
−
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:'''
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:''' has both a membrane-spanning and an ATP-binding domain {{PubMed\|10092453}}
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[BmrC]]-[[BmrD]] [http://www.ncbi.nlm.nih.gov/pubmed/19167342?ordinalpos=286&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum PubMed]
−
−	* '''[[Localization]]:''' cell membrane {{PubMed\|10092453}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU09710&redirect=T BSU09710]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/O07550 O07550]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU09710]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[bmrB]]-[[bmrC]]-[[bmrD]]'' {{PubMed\|25217586}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yheI_1045318_1047075_1 bmrC] {{PubMed\|22383849}}
−
−	* '''Sigma factor:'''
−
−	* '''Regulation:'''
−	** induced in response to antibiotics that target protein synthesis ([[BmrB]]) {{PubMed\|25217586}}
−	** ''[[bmrC]]-[[bmrD]]'' expression only occurs during the late-exponential and stationary growth stages, irrespective of the timing of the antibiotic challenge ([[AbrB]]) {{PubMed\|25217586}}
−
−	* '''Regulatory mechanism:'''
−	** [[AbrB]]: transcription repression {{PubMed\|25217586}}
−	** [[BmrB]]: transcriptional attenuation {{PubMed\|25217586}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~<pubmed>19167342,10092453,16487324 25217586 21602923</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 107: / Line 107: @@
 =Expression and regulation=
-* '''Operon:'''
+* '''Operon:''' ''[[bmrB]]-[[bmrC]]-[[bmrD]]'' {{PubMed|25217586}}
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yheI_1045318_1047075_1 bmrC] {{PubMed|22383849}}
@@ Line 114: / Line 114: @@
 * '''Regulation:'''
-** induced in response to antibiotics that target protein synthesis {{PubMed|25217586}}
+** induced in response to antibiotics that target protein synthesis ([[BmrB]]) {{PubMed|25217586}}
 * '''Regulatory mechanism:'''
 * '''Additional information:'''

@@ Line 36: / Line 36: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 118: / Line 114: @@
 * '''Regulation:'''
 * '''Regulatory mechanism:'''
@@ Line 142: / Line 139: @@
 =References=
-'''Additional publications:''' {{PubMed|21602923}}
+<pubmed>19167342,10092453,16487324 25217586 21602923</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 46: / Line 46: @@
 {{SubtiWiki category|[[resistance against toxins/ antibiotics]]}},
 {{SubtiWiki category|[[membrane proteins]]}},
-{{SubtiWiki category|[[Sporulation#Sporulation_proteins/_other|sporulation proteins]]}}
+{{SubtiWiki category|[[sporulation proteins]]}}
 = This gene is a member of the following [[regulons]] =

@@ Line 46: / Line 46: @@
 {{SubtiWiki category|[[resistance against toxins/ antibiotics]]}},
 {{SubtiWiki category|[[membrane proteins]]}},
-{{SubtiWiki category|[[sporulation/ other]]}}
+{{SubtiWiki category|[[Sporulation#Sporulation_proteins/_other|sporulation proteins]]}}
 = This gene is a member of the following [[regulons]] =

@@ Line 59: / Line 59: @@
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 95: / Line 96: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 15: / Line 15: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU09710 bmrC]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/BmrC BmrC]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=BmrC BmrC]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 64 kDa, 6.252

@@ Line 28: / Line 28: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yheI_1045318_1047075_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:bmrC_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yheI_1045318_1047075_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:bmrC_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU09710]]
 |-
 |}

@@ Line 23: / Line 23: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yheJ]]'', ''[[bmrD]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU09710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU09710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU09710 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU09710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU09710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU09710 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:yheI_context.gif]]