liaF

liaF
168

inhibitor of LiaS kinase activity

Locus
BSU_33100
Molecular weight
26.88 kDa
Isoelectric point
9.21
Protein length
241 aaSequenceBlast
Gene length
726 bpSequenceBlast
Function
control of LiaR activity
Product
negative effector of LiaS
Essential
no
Synonyms
liaF, yvqF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4758 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,396,114 → 3,396,839
The protein
Catalyzed reaction/ biological activity
inhibitor of LiaS kinase activity, maintains LiaS in the phosphatase state in the absence of the stress signal PubMed
Structure
O32199 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
liaG-liaF-liaS-liaR
Description
PubMed
Regulation
''liaG'': constitutive
Regulatory mechanism
LiaR: activation, PubMed, in liaR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

liaG→liaR

2025-04-03 08:27:16

ghost

105

2f16b4fd354512d8414b5b6145620bdeaa475d46

AF84222759CC1E14AC8022D48DBA6522494204CA

Genes
liaI-liaH-liaG-liaF-liaS-liaR
Description
PubMed
Regulation
''liaG'': constitutive
Open in new tab

liaI→liaR

2025-04-03 08:12:04

ghost

126

844f52131490c84c9a0558a221a24520579ef3fd

F37C9323D2117C9590CDC8EC3E6B0E3F58AFC1F7

Biological materials
Mutant
MGNA-B037 (yvqF::erm), available at the NBRP B. subtilis, Japan
BKE33100 (ΔliaF::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCCTGGTGTCCGCCTCC,  downstream forward: _UP4_GGTGATGTGGATGTGAAGTA
BKK33100 (ΔliaF::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCCTGGTGTCCGCCTCC,  downstream forward: _UP4_GGTGATGTGGATGTGAAGTA
References
Reviews
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Original Publications
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C107A958DFA2B0DA4837E2F9F648CD329A3116AC

Page visits: 3611

Time of last update: 2025-04-06 20:13:49

Author of last update: Jstuelk