catR

catR
168

MarR/DUF24 family transcription repressor of the catD-catE operon

Locus
BSU_33680
Molecular weight
26.99 kDa
Isoelectric point
9.89
Protein length
108 aaSequenceBlast
Gene length
327 bpSequenceBlast
Function
resistance against oxidative and electrophile stress
Product
MarR/DUF24 family transcription repressor
Essential
no
Synonyms
catR, yvaP
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1733 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,457,615  3,457,941
Phenotypes of a mutant
increased resistance to catechol and quinones PubMed
The protein
Catalyzed reaction/ biological activity
MarR/DUF24 family transcription repressor of the catD-catE operon PubMed
Protein family
MarR/DUF24 family
Domains
HTH hxlR-type domain (aa 7-106) (according to UniProt)
Structure
5HS7 (PDB) (YodB, 46% identity) PubMed
O32238 (AlphaFold)
Modification
in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of catD-catE) PubMed
Paralogous protein(s)
YodB
Expression and Regulation
Operons
Genes
catR
Description
PubMed
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catR

2025-02-22 02:42:16

Jstuelk

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b74cbd1e1d69bbfb10ee5cd123dced4840e80e91

3B324851E1DAE002ED88E618494C6756348DA726

Biological materials
Mutant
MGNA-A451 (yvaP::erm), available at the NBRP B. subtilis, Japan
BKE33680 (catR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACTTTTCACCTCGTCTG,  downstream forward: _UP4_TAATTGCTAAAATGGTTCTG
BKK33680 (catR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACTTTTCACCTCGTCTG,  downstream forward: _UP4_TAATTGCTAAAATGGTTCTG
Labs working on this gene/protein
Haike Antelmann,University of Greifswald, Germany
References
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5B9C4932B2E76D6B8F6BDB640D1ADEE28F488FAD

Page visits: 3957

Time of last update: 2025-03-14 11:43:09

Author of last update: Melvin.boenninger