sufD
168

FeS scaffold, synthesis of Fe-S-clusters

Locus

BSU_32700

Molecular weight

48.13 kDa

Isoelectric point

4.95

Protein length

437 aaSequenceBlast

Gene length

1314 bpSequenceBlast

Function

synthesis of Fe-S-clusters

Product

FeS scaffold

Essential

yes

Synonyms

sufD, yurX

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0719 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

3,358,664 3,359,977

Phenotypes of a mutant

essential PubMed

the mutant is viable and Fe-S clusters are dispensable if IspG and IspH from the MEP pathway for isoprenoid biosynthesis are bypassed by a heterologous mevalonate pathway which allows B. subtilis to synthesize isopentenyl diphosphate and diphosphomevalonate PubMed

The protein

Catalyzed reaction/ biological activity

synthesis of Fe-S-clusters (the SufB-SufC-SufD complex) PubMed

Protein family

UPF0051 (ycf24) family (with SufB, according to UniProt)

Structure

5AWF (PDB) (from E. coli, the SufB-SufC-SufD complex, 24% identity) PubMed

O32165 (AlphaFold)

Localization

cytoplasm (homogeneous) PubMed

Additional information

belongs to the 100 most abundant proteins PubMed