KhtS

• Description: modulator of KhtU activity
  
  

Gene name	yhaS
Synonyms
Essential	no
Product	modulator of YhaU activity
Function	control of potassium ion efflux
Gene expression levels in SubtiExpress: khtS
Metabolic function and regulation of this protein in SubtiPathways: KhtS
MW, pI	12 kDa, 7.023
Gene length, protein length	336 bp, 112 aa
Immediate neighbours	khtT, yhaR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

metal ion homeostasis (K, Na, Ca, Mg)

The gene

Basic information

• Locus tag: BSU09870

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O07534

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: khtS-khtT-khtU PubMed

• Expression browser: khtS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • GP2078 (khtS-khtT-khtU::aphA3), available in Jörg Stülke's lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Pete Chandrangsu, Renata Dusi, Chris J Hamilton, John D Helmann
Methylglyoxal resistance in Bacillus subtilis: contributions of bacillithiol-dependent and independent pathways.
Mol Microbiol: 2014, 91(4);706-15
[PubMed:24330391] [WorldCat.org] [DOI] (I p)

Makoto Fujisawa, Yuko Wada, Masahiro Ito
Modulation of the K+ efflux activity of Bacillus subtilis YhaU by YhaT and the C-terminal region of YhaS.
FEMS Microbiol Lett: 2004, 231(2);211-7
[PubMed:14987767] [WorldCat.org] [DOI] (P p)