ecfA1

ecfA1
168

ATP-binding A1 component of ECF transporters

Locus
BSU_01450
Molecular weight
31.31 kDa
Isoelectric point
4.77
Protein length
281 aaSequenceBlast
Gene length
846 bpSequenceBlast
Function
uptake of micronutrients
Product
ECF transporter (ATP-binding protein)
Essential
no
E.C.
3.6.3.-
Synonyms
ybxA, ybaD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1122 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
150,443 → 151,288
The protein
Protein family
ABC transporter superfamily (according to UniProt)
Domains
ABC transporter domain (aa 7-242) (according to UniProt)
Structure
4HUQ (PDB) (EcfA1-EcfA2-EcfT-FolT complex of Lactobacillus brevis), PubMed
P40735 (AlphaFold)
Paralogous protein(s)
EcfA2
Localization
membrane associated (via EcfT) PubMed
Biological materials
Mutant
BKE01450 (ΔecfA1::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGGAAAACCGGCCTCCTC,  downstream forward: _UP4_AAGATGTAGAGCATCGCTAT
BKK01450 (ΔecfA1::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGGAAAACCGGCCTCCTC,  downstream forward: _UP4_AAGATGTAGAGCATCGCTAT
BP1149 (ecfA1-ecfA2-ecfT::cat trp+) available at Jörg Stülke's and Fabian Commichau's labs
References
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Time of last update: 2025-04-02 13:38:14

Author of last update: Jstuelk